We Are Not Immune: Racial and Ethnic Disparities in Autoimmune Liver Diseases
Sign Up to like & getrecommendations! Published in 2021 at "Hepatology"
DOI: 10.1002/hep.31985
Abstract: Autoimmune liver diseases are attributed to a complex interplay of biologic, acquired, and environmental factors. Increased prevalence, later stage at presentation, worse response to standard therapy, and transplant‐related disparities have all been reported in racial… read more here.
Keywords: autoimmune liver; liver diseases; ethnic disparities; racial ethnic ... See more keywords
Sex-related factors in autoimmune liver diseases
Sign Up to like & getrecommendations! Published in 2018 at "Seminars in Immunopathology"
DOI: 10.1007/s00281-018-0715-8
Abstract: Autoimmune diseases are a broad range of diseases in which the immune system produces an inappropriate response to self-antigens. This results in inflammation, damage, or dysfunction of tissues and/or organs. Many autoimmune diseases are more… read more here.
Keywords: autoimmune liver; liver diseases; sex; autoimmune diseases ... See more keywords
Support of precision medicine through risk-stratification in autoimmune liver diseases - histology, scoring systems, and non-invasive markers.
Sign Up to like & getrecommendations! Published in 2018 at "Autoimmunity reviews"
DOI: 10.1016/j.autrev.2018.02.013
Abstract: Autoimmune liver diseases (AILDs) are complex conditions, which arise from the interaction between a genetic susceptibility and unknown environmental triggers. They represent a relevant cause of liver failure and liver transplantation worldwide. As a testimony… read more here.
Keywords: medicine; risk; autoimmune liver; liver diseases ... See more keywords
Single cell profiling of circulating autoreactive CD4 T cells from patients with autoimmune liver diseases suggests tissue imprinting
Sign Up to like & getrecommendations! Published in 2025 at "Nature Communications"
DOI: 10.1038/s41467-025-56363-2
Abstract: Autoimmune liver diseases (AILD) involve dysregulated CD4 T cell responses against liver self-antigens, but how these autoreactive T cells relate to liver tissue pathology remains unclear. Here we perform single-cell transcriptomic and T cell receptor… read more here.
Keywords: autoimmune liver; cd4 cells; autoreactive cd4; cell ... See more keywords
Quantitative multiparametric MRI as a non-invasive stratification tool in children and adolescents with autoimmune liver disease
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-94754-9
Abstract: Autoimmune hepatitis (AIH) and autoimmune sclerosing cholangitis (ASC) are two very closely related autoimmune liver diseases with overlapping clinical features and similar management strategies. The purpose of this study was to assess the utility of… read more here.
Keywords: mrcp; autoimmune liver; asc aih; mri non ... See more keywords
Systemic PCSK9 elevation characterises autoimmune liver disease across sexes
Sign Up to like & getrecommendations! Published in 2025 at "Scientific Reports"
DOI: 10.1038/s41598-025-28881-y
Abstract: Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a key regulator of serum cholesterol. Its expression is particularly abundant in hepatocytes, yet its role in autoimmune liver diseases remains unclear. Here we investigated serum PCSK9 levels… read more here.
Keywords: autoimmune liver; liver disease; pcsk9 levels; pcsk9 ... See more keywords
The Contribution of B Cells in Autoimmune Liver Diseases.
Sign Up to like & getrecommendations! Published in 2019 at "Seminars in liver disease"
DOI: 10.1055/s-0039-1688751
Abstract: Autoreactive B cells can promote autoimmunity through antigen presentation to autoreactive T cells, production of autoantibodies, generation of cytokines promoting T cell activation and differentiation, and inhibition of regulatory T cells and B cells. Here,… read more here.
Keywords: autoimmune liver; liver diseases; cells autoimmune; cell ... See more keywords
The prevalence and disease course of autoimmune liver diseases in Greenland
Sign Up to like & getrecommendations! Published in 2024 at "International Journal of Circumpolar Health"
DOI: 10.1080/22423982.2024.2327693
Abstract: ABSTRACT Autoimmune liver diseases are rare serious diseases causing chronic inflammation and fibrosis in the liver parenchyma and bile ducts. Yet, the prevalence and burden of autoimmune liver diseases are largely unexplored in Arctic native… read more here.
Keywords: autoimmune liver; liver diseases; histology; liver ... See more keywords
Intestinal homeostasis in autoimmune liver diseases
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DOI: 10.1097/cm9.0000000000002291
Abstract: Abstract Intestinal homeostasis depends on complex interactions between the gut microbiota and host immune system. Emerging evidence indicates that the intestinal microbiota is a key player in autoimmune liver disease (AILD). Autoimmune hepatitis, primary biliary… read more here.
Keywords: homeostasis autoimmune; intestinal homeostasis; homeostasis; autoimmune liver ... See more keywords
Causal mediation of immune cells in autoimmune liver diseases and oral cancer risk: a mendelian randomization study.
Sign Up to like & getrecommendations! Published in 2025 at "International journal of surgery"
DOI: 10.1097/js9.0000000000004072
Abstract: BACKGROUND Emerging evidence suggests shared immune pathways between autoimmune liver diseases (AILDs) and oral cavity cancer (OCC), yet their causal interdependence remains poorly characterized. METHODS This study employs bidirectional Mendelian randomization (MR) with mediation analysis… read more here.
Keywords: autoimmune liver; liver diseases; risk; mediation ... See more keywords
Increased Posttransplant Mortality for Autoimmune Hepatitis Compared With Other Autoimmune Liver Diseases
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Gastroenterology"
DOI: 10.1097/mcg.0000000000001271
Abstract: Goals: We sought to compare posttransplant outcomes between autoimmune liver disease. Background: Autoimmune liver diseases, namely primary biliary cholangitis (PBC), primary sclerosing cholangitis (PSC), and autoimmune hepatitis (AIH) generally have favorable posttransplant outcomes. PSC is… read more here.
Keywords: autoimmune hepatitis; compared autoimmune; autoimmune liver; increased posttransplant ... See more keywords