Targeting Bruton’s Tyrosine Kinase in Inflammatory and Autoimmune Pathologies
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2021.668131
Abstract: Bruton’s tyrosine kinase (BTK) was discovered due to its importance in B cell development, and it has a critical role in signal transduction downstream of the B cell receptor (BCR). Targeting of BTK with small… read more here.
Keywords: autoimmune pathologies; btk; inflammatory autoimmune; bruton tyrosine ... See more keywords
The Role of Immune Checkpoint Molecules on Macrophages in Cancer, Infection, and Autoimmune Pathologies
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.837645
Abstract: Immune checkpoint inhibitors have revolutionized immunotherapy against various cancers over the last decade. The use of checkpoint inhibitors results in remarkable re-activation of patients’ immune system, but is also associated with significant adverse events. In… read more here.
Keywords: macrophage; checkpoint; immune checkpoint; checkpoint molecules ... See more keywords