Autoimmune pulmonary alveolar proteinosis in an adolescent successfully treated with inhaled rhGM-CSF (molgramostim)
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DOI: 10.1016/j.rmcr.2018.02.005
Abstract: Autoimmune pulmonary alveolar proteinosis (aPAP) is a rare parenchymal lung disease characterized by accumulation of surfactant in the airways with high levels of granulocyte-macrophage colony stimulating factor (GM-CSF) antibodies in blood. Disease leads to hypoxemic… read more here.
Keywords: pulmonary alveolar; csf; alveolar proteinosis; successfully treated ... See more keywords
Exacerbation of autoimmune pulmonary alveolar proteinosis that improved with lone treatment of complicating nontuberculous mycobacterial infection: A case report
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DOI: 10.1016/j.rmcr.2021.101521
Abstract: Herein, we present the case of a 63-year-old man with autoimmune pulmonary alveolar proteinosis (APAP) complicated by Mycobacterium avium complex (MAC) infection. APAP was diagnosed based on serum anti-granulocyte-macrophage colony-stimulating factor antibody, bronchoalveolar lavage fluid… read more here.
Keywords: pulmonary alveolar; case; alveolar proteinosis; autoimmune pulmonary ... See more keywords
Peripheral alveolar nitric oxide concentration reflects alveolar inflammation in autoimmune pulmonary alveolar proteinosis
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DOI: 10.1183/23120541.00071-2017
Abstract: Autoimmune pulmonary alveolar proteinosis (aPAP) is caused by an excess of autoantibodies against granulocyte-macrophage colony-stimulating factor (GM-CSF). In this situation, the clearance of intracellular debris in alveolar macrophages is impaired, and the alveolar spaces are… read more here.
Keywords: pulmonary alveolar; inflammation; alveolar proteinosis; autoimmune pulmonary ... See more keywords
Autoimmune Pulmonary Alveolar Proteinosis with Suspected Exacerbation after Osimertinib Administration for Lung Cancer
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DOI: 10.2169/internalmedicine.0256-22
Abstract: A 46-year-old woman with lung cancer who received chemotherapy was admitted to our hospital for lower-lobe bilateral ground-glass opacity (GGO). GGO developed after the lung cancer diagnosis, deteriorated after the initiation of osimertinib, and incompletely… read more here.
Keywords: lung cancer; pulmonary alveolar; osimertinib; autoimmune pulmonary ... See more keywords
A Case of Autoimmune Pulmonary Alveolar Proteinosis that Improved after a COVID-19 Episode.
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DOI: 10.2169/internalmedicine.1592-23
Abstract: Autoimmune pulmonary alveolar proteinosis (APAP) is caused by macrophage dysfunction owing to the presence of anti-granulocyte-macrophage colony-stimulating factor (GM-CSF) autoantibodies. A 77-year-old man with APAP was referred to our hospital for whole-lung lavage (WLL) due… read more here.
Keywords: pulmonary alveolar; alveolar proteinosis; apap; autoimmune pulmonary ... See more keywords