A Transmembrane Protein WAI-B2 Confers Multiple Disease Resistance in Wheat by Activating Autoimmunity.
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DOI: 10.1002/advs.202511576
Abstract: Wheat (Triticum aestivum L.) is one of the world's most important food crops and its production is frequently threatened by diseases caused by several biotrophic pathogens, including stripe rust, leaf rust, stem rust and powdery… read more here.
Keywords: resistance; wheat; autoimmunity; transmembrane protein ... See more keywords
High prevalence of diabetes‐specific autoimmunity in first‐degree relatives of Sardinian patients with type 1 diabetes
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DOI: 10.1002/dmrr.2864
Abstract: The incidence of type 1 diabetes mellitus (T1DM) in Sardinia is among the highest in the world (44.8 cases/100,000 person‐years). Recommendations of the Immunology of Diabetes Society advise evaluating autoantibody positivity in first‐degree relatives (FDRs)… read more here.
Keywords: degree relatives; first degree; high prevalence; type diabetes ... See more keywords
Fatty acid status in infancy is associated with the risk of type 1 diabetes-associated autoimmunity
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DOI: 10.1007/s00125-017-4280-9
Abstract: Aims/hypothesisWe investigated the association of early serum fatty acid composition with the risk of type 1 diabetes-associated autoimmunity. Our hypothesis was that fatty acid status during infancy is related to type 1 diabetes-associated autoimmunity and… read more here.
Keywords: risk; fatty acid; type diabetes; autoimmunity ... See more keywords
γδ T cells in rheumatic diseases: from fundamental mechanisms to autoimmunity
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DOI: 10.1007/s00281-019-00752-5
Abstract: The innate and adaptive arms of the immune system tightly regulate immune responses in order to maintain homeostasis and host defense. The interaction between those two systems is critical in the activation and suppression of… read more here.
Keywords: diseases fundamental; cells rheumatic; rheumatic diseases; autoimmunity cells ... See more keywords
Autoimmunity in plants
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DOI: 10.1007/s00425-018-2956-0
Abstract: Main conclusionAttenuation in the activity of the negative regulators or the hyperactivity of plant innate immune receptors often causes ectopic defense activation manifested in severe growth retardation and spontaneous lesion formations, referred to as autoimmunity.… read more here.
Keywords: autoimmunity plants; plant; defense; host ... See more keywords
Two Decades of Publications in Journals Dedicated to Autoimmunity: A Bibliometric Analysis of the Autoimmunity Field from 2004 to 2023
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DOI: 10.1007/s10238-024-01369-1
Abstract: To carry out an in-depth analysis of the scientific research on autoimmunity, we performed the first bibliometric analysis focusing on publications in journals dedicated to autoimmunity (JDTA) indexed by science citation index during the period… read more here.
Keywords: field; 2004 2023; analysis; bibliometric analysis ... See more keywords
Premature ovarian insufficiency (POI) and autoimmunity-an update appraisal
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DOI: 10.1007/s10815-019-01572-0
Abstract: Primary ovarian insufficiency (POI) represents ovarian dysfunction related to very early aging of the ovaries. While the cause of POI in a majority of clinical cases remains undefined, autoimmunity is responsible for approximately 4–30% of… read more here.
Keywords: poi; poi autoimmunity; ovarian insufficiency; autoimmunity ... See more keywords
Autoinflammation Masquerading as Autoimmunity in an Adult with Heterozygous p.E250K PSTPIP1 Mutation
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DOI: 10.1007/s10875-019-00646-z
Abstract: To the Editor, PSTPIP-1-associated myeloid-related proteinemia inflammatory syndrome (PAMI) is a rare autoinflammatory disease that typically presents in childhood, characterized by high serum levels of zinc and the alarmin calprotectin. It is associated with the… read more here.
Keywords: autoimmunity adult; adult heterozygous; pstpip1; autoinflammation masquerading ... See more keywords
Phenotypic and Immunological Characterization of Patients with Activated PI3Kδ Syndrome 1 Presenting with Autoimmunity
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DOI: 10.1007/s10875-024-01705-w
Abstract: Autoimmunity is a significant feature of APDS1 patients. We aimed to explore the pathogenic immune phenotype and possible mechanisms of autoimmunity in APDS1 patients. The clinical records and laboratory data of 42 APDS1 patients were… read more here.
Keywords: apds1 patients; patients autoimmunity; autoimmunity; memory cells ... See more keywords
Tolerogenic Nanoparticles to Treat Islet Autoimmunity
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DOI: 10.1007/s11892-017-0914-z
Abstract: Purpose of ReviewThe current standard therapy for type 1 diabetes (T1D) is insulin replacement. Autoimmune diseases are typically treated with broad immunosuppression, but this has multiple disadvantages. Induction of antigen-specific tolerance is preferable. The application… read more here.
Keywords: islet autoimmunity; nanoparticles treat; tolerogenic nanoparticles; tolerance ... See more keywords
Obsessive-Compulsive Disorder: Autoimmunity and Neuroinflammation
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DOI: 10.1007/s11920-019-1062-8
Abstract: Purpose of ReviewHere, we propose to review the immuno-inflammatory hypothesis in OCD given the concurrent incidence of autoimmune comorbidities, infectious stigma, and raised levels of inflammatory markers in a significant subset of patients. A better… read more here.
Keywords: autoimmunity neuroinflammation; compulsive disorder; obsessive compulsive; disorder autoimmunity ... See more keywords