High prevalence of diabetes‐specific autoimmunity in first‐degree relatives of Sardinian patients with type 1 diabetes
Sign Up to like & getrecommendations! Published in 2017 at "Diabetes/Metabolism Research and Reviews"
DOI: 10.1002/dmrr.2864
Abstract: The incidence of type 1 diabetes mellitus (T1DM) in Sardinia is among the highest in the world (44.8 cases/100,000 person‐years). Recommendations of the Immunology of Diabetes Society advise evaluating autoantibody positivity in first‐degree relatives (FDRs)… read more here.
Keywords: degree relatives; first degree; high prevalence; type diabetes ... See more keywords
Fatty acid status in infancy is associated with the risk of type 1 diabetes-associated autoimmunity
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DOI: 10.1007/s00125-017-4280-9
Abstract: Aims/hypothesisWe investigated the association of early serum fatty acid composition with the risk of type 1 diabetes-associated autoimmunity. Our hypothesis was that fatty acid status during infancy is related to type 1 diabetes-associated autoimmunity and… read more here.
Keywords: risk; fatty acid; type diabetes; autoimmunity ... See more keywords
γδ T cells in rheumatic diseases: from fundamental mechanisms to autoimmunity
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DOI: 10.1007/s00281-019-00752-5
Abstract: The innate and adaptive arms of the immune system tightly regulate immune responses in order to maintain homeostasis and host defense. The interaction between those two systems is critical in the activation and suppression of… read more here.
Keywords: diseases fundamental; cells rheumatic; rheumatic diseases; autoimmunity cells ... See more keywords
Autoimmunity in plants
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DOI: 10.1007/s00425-018-2956-0
Abstract: Main conclusionAttenuation in the activity of the negative regulators or the hyperactivity of plant innate immune receptors often causes ectopic defense activation manifested in severe growth retardation and spontaneous lesion formations, referred to as autoimmunity.… read more here.
Keywords: autoimmunity plants; plant; defense; host ... See more keywords
Premature ovarian insufficiency (POI) and autoimmunity-an update appraisal
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DOI: 10.1007/s10815-019-01572-0
Abstract: Primary ovarian insufficiency (POI) represents ovarian dysfunction related to very early aging of the ovaries. While the cause of POI in a majority of clinical cases remains undefined, autoimmunity is responsible for approximately 4–30% of… read more here.
Keywords: poi; poi autoimmunity; ovarian insufficiency; autoimmunity ... See more keywords
Autoinflammation Masquerading as Autoimmunity in an Adult with Heterozygous p.E250K PSTPIP1 Mutation
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Immunology"
DOI: 10.1007/s10875-019-00646-z
Abstract: To the Editor, PSTPIP-1-associated myeloid-related proteinemia inflammatory syndrome (PAMI) is a rare autoinflammatory disease that typically presents in childhood, characterized by high serum levels of zinc and the alarmin calprotectin. It is associated with the… read more here.
Keywords: autoimmunity adult; adult heterozygous; pstpip1; autoinflammation masquerading ... See more keywords
Tolerogenic Nanoparticles to Treat Islet Autoimmunity
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DOI: 10.1007/s11892-017-0914-z
Abstract: Purpose of ReviewThe current standard therapy for type 1 diabetes (T1D) is insulin replacement. Autoimmune diseases are typically treated with broad immunosuppression, but this has multiple disadvantages. Induction of antigen-specific tolerance is preferable. The application… read more here.
Keywords: islet autoimmunity; nanoparticles treat; tolerogenic nanoparticles; tolerance ... See more keywords
Obsessive-Compulsive Disorder: Autoimmunity and Neuroinflammation
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DOI: 10.1007/s11920-019-1062-8
Abstract: Purpose of ReviewHere, we propose to review the immuno-inflammatory hypothesis in OCD given the concurrent incidence of autoimmune comorbidities, infectious stigma, and raised levels of inflammatory markers in a significant subset of patients. A better… read more here.
Keywords: autoimmunity neuroinflammation; compulsive disorder; obsessive compulsive; disorder autoimmunity ... See more keywords
TPO antibody in euthyroid pregnant women and cognitive ability in the offspring: a focused review
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DOI: 10.1007/s40618-021-01664-8
Abstract: A link between maternal thyroid dysfunction during pregnancy and the risk of cognitive and behavioral problems in the offspring has previously been established; however, the potential effects of maternal thyroid autoimmunity on neurodevelopment in the… read more here.
Keywords: maternal thyroid; thyroid autoimmunity; review; tpo antibody ... See more keywords
Recent advancements in role of TAM receptors on efferocytosis, viral infection, autoimmunity, and tissue repair.
Sign Up to like & getrecommendations! Published in 2020 at "International review of cell and molecular biology"
DOI: 10.1016/bs.ircmb.2020.09.008
Abstract: Evolutionarily conserved highly regulated process of apoptosis has been a major physiological process throughout the entire evolutionary history of living beings that has impacted the process of evolution itself. One of the key features of… read more here.
Keywords: tissue repair; process; autoimmunity; advancements role ... See more keywords
Autoimmunity, Autoinflammation, and Infection in Uveitis.
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DOI: 10.1016/j.ajo.2018.02.019
Abstract: PURPOSE To review the pathogenesis of uveitis in light of recent advances in our understanding of innate and adaptive immune responses and their regulation. DESIGN Perspective. METHODS Methods included a review of prevailing views on… read more here.
Keywords: infection uveitis; pathogenesis uveitis; infection; autoimmunity ... See more keywords