Transition from Syringe to Autoinjector Based on Bridging Pharmacokinetics and Pharmacodynamics of the P2Y12 Receptor Antagonist Selatogrel in Healthy Subjects
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DOI: 10.1007/s40262-021-01097-9
Abstract: Selatogrel is a potent, reversible, and selective antagonist of the platelet P2Y12 receptor currently developed for the treatment of acute myocardial infarction (AMI). In the completed Phase I/II studies, selatogrel was subcutaneously (s.c.) administered as… read more here.
Keywords: selatogrel; phase; formulation; treatment ... See more keywords
Ease of use of two autoinjectors in patients with multiple sclerosis treated with interferon beta-1a subcutaneously three times weekly: results of the randomized, crossover REDEFINE study
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DOI: 10.1080/17425247.2018.1407755
Abstract: ABSTRACT Background: For interferon beta-1a subcutaneously three times weekly (IFN β-1a SC tiw), administration options include manually injected prefilled syringes; a preassembled, single-use autoinjector; and a reusable autoinjector. This study evaluated patient-perceived ease of use… read more here.
Keywords: use; autoinjector; use two; interferon beta ... See more keywords
Patients’ and nurses’ preferences for autoinjectors for rheumatoid arthritis: results of a European survey
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DOI: 10.2147/ppa.s169339
Abstract: Purpose This survey investigated patients’ and nurses’ preferences among four different autoinjectors used for subcutaneous delivery of medication for rheumatoid arthritis (RA). Methods In a multinational survey in five countries, 200 patients with RA and… read more here.
Keywords: autoinjector; patients nurses; survey; injection ... See more keywords