Fast and automated characterization of monoclonal antibody minor variants from cell cultures by combined Protein-A and multi-dimensional LC/MS methodologies.
Sign Up to like & getrecommendations! Published in 2020 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.0c01250
Abstract: Monitoring of post-translational modifications (PTMs) in therapeutic monoclonal antibodies (mAbs) is essential during their production in both upstream and downstream processes. However, characterization of PTMs using conventional peptide mapping procedure requires time-consuming and labor-intensive offline… read more here.
Keywords: automated characterization; multi dimensional; fast automated; cell ... See more keywords
Automated Characterization of Anthropomorphicity of Prosthetic Feet Fitted to Bone-Anchored Transtibial Prosthesis
Sign Up to like & getrecommendations! Published in 2019 at "IEEE Transactions on Biomedical Engineering"
DOI: 10.1109/tbme.2019.2904713
Abstract: Objective: This study describes differentiating prosthetic feet designs fitted to bone-anchored transtibial prostheses based on an automated characterization of ankle stiffness profile relying on direct loading measurements. The objectives were, first, to present a process… read more here.
Keywords: characterization; prosthetic feet; anthropomorphicity; bone anchored ... See more keywords