Automated Flow Synthesis of Peptide–PNA Conjugates
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DOI: 10.1021/acscentsci.1c01019
Abstract: Antisense peptide nucleic acids (PNAs) have yet to translate to the clinic because of poor cellular uptake, limited solubility, and rapid elimination. Cell-penetrating peptides (CPPs) covalently attached to PNAs may facilitate clinical development by improving… read more here.
Keywords: peptide; pna conjugates; automated flow; peptide pna ... See more keywords
Determination of Rhenium in Seawater from the Jiulong River Estuary and Taiwan Strait, China by Automated Flow Injection Inductively Coupled Plasma–Mass Spectrometry
Sign Up to like & getrecommendations! Published in 2017 at "Analytical Letters"
DOI: 10.1080/00032719.2016.1233244
Abstract: ABSTRACT A novel and automated flow injection (FI) system using a commercially available anion-exchange resin was developed for the online determination of rhenium in seawater by inductively coupled plasma–mass spectrometry (ICP–MS). The flow rate, reagent… read more here.
Keywords: automated flow; rhenium seawater; flow injection; rhenium ... See more keywords
Synthesis of proteins by automated flow chemistry
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DOI: 10.1126/science.abb2491
Abstract: Fully synthetic whole proteins in reach Solid-phase peptide synthesis of homogeneous peptides longer than about 50 amino acids has been a long-standing challenge because of inefficient coupling and side reactions. Hartrampf et al. used an… read more here.
Keywords: automated flow; flow chemistry; amino acids; chemistry ... See more keywords
Drug Discovery Testing Compounds in Patient Samples by Automated Flow Cytometry
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DOI: 10.1177/2472630317700346
Abstract: Functional ex vivo assays that predict a patient’s clinical response to anticancer drugs for guiding cancer treatment have long been a goal, but few have yet proved to be reliable. To address this, we have… read more here.
Keywords: drug; drug discovery; automated flow; flow cytometry ... See more keywords