Miniaturized and Automated Synthesis of Biomolecules-Overview and Perspectives.
Sign Up to like & getrecommendations! Published in 2019 at "Advanced materials"
DOI: 10.1002/adma.201806656
Abstract: Chemical synthesis is performed by reacting different chemical building blocks with defined stoichiometry, while meeting additional conditions, such as temperature and reaction time. Such a procedure is especially suited for automation and miniaturization. Life sciences… read more here.
Keywords: miniaturized automated; automated synthesis; biomolecules overview; synthesis biomolecules ... See more keywords
Automated synthesis of decentralized controllers for robot swarms from high-level temporal logic specifications
Sign Up to like & getrecommendations! Published in 2020 at "Autonomous Robots"
DOI: 10.1007/s10514-019-09861-4
Abstract: The majority of work in the field of swarm robotics focuses on the bottom-up design of local rules for individual robots that create emergent swarm behaviors. In this paper, we take a top-down approach and… read more here.
Keywords: controllers robot; synthesis decentralized; automated synthesis; decentralized controllers ... See more keywords
An automated synthesis method for 68Ga-labelled ubiquicidin 29–41
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Radioanalytical and Nuclear Chemistry"
DOI: 10.1007/s10967-019-06910-1
Abstract: Published methods for radiolabelling of 1,4,7-triazacyclononane-1,4,7-triacetic acid ubiquicidin (NOTA-UBI) 29–41 to date describe manual or kit-based procedures. The purpose of this study was to develop an automated synthesis method for the synthesis of [68Ga]Ga-NOTA-UBI. NOTA-UBI… read more here.
Keywords: nota ubi; automated synthesis; synthesis method; method 68ga ... See more keywords
Automated synthesis of steady-state continuous processes using reinforcement learning
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers of Chemical Science and Engineering"
DOI: 10.1007/s11705-021-2055-9
Abstract: Automated flowsheet synthesis is an important field in computer-aided process engineering. The present work demonstrates how reinforcement learning can be used for automated flowsheet synthesis without any heuristics or prior knowledge of conceptual design. The… read more here.
Keywords: automated synthesis; flowsheet synthesis; reinforcement learning; steady state ... See more keywords
Using automated synthesis to understand the role of side chains on molecular charge transport.
Sign Up to like & getrecommendations! Published in 2022 at "Nature communications"
DOI: 10.1038/s41467-022-29796-2
Abstract: The development of next-generation organic electronic materials critically relies on understanding structure-function relationships in conjugated polymers. However, unlocking the full potential of organic materials requires access to their vast chemical space while efficiently managing the… read more here.
Keywords: charge transport; automated synthesis; side chains; side ... See more keywords
A vending machine for drug-like molecules – automated synthesis of virtual screening hits
Sign Up to like & getrecommendations! Published in 2022 at "Chemical Science"
DOI: 10.1039/d2sc05182f
Abstract: As a result of high false positive rates in virtual screening campaigns, prospective hits must be synthesised for validation. When done manually, this is a time consuming and laborious process. Large “on-demand” virtual libraries (>7… read more here.
Keywords: virtual screening; drug like; automated synthesis; screening hits ... See more keywords