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Published in 2020 at "Medicina clinica"
DOI: 10.1016/j.medcli.2020.07.025
Abstract: OBJECTIVE To analyse the differences in the cardio-metabolic profile of patients with primary aldosteronism (PA) and autonomous cortisol secretion (ACS) matched by age and sex. METHODS Case-control study; cases of PA without associated ACS and… read more here.
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Published in 2024 at "Hypertension Research"
DOI: 10.1038/s41440-024-01933-y
Abstract: Patients with adrenal aldosterone-producing adenomas (APA) face elevated cardiovascular risks, especially when cortisol is co-secreted, yet the impact on muscle health remains unclear. Myosteatosis, characterized by fatty infiltration into muscles, is linked to cardiometabolic diseases… read more here.
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Published in 2022 at "Clinical Endocrinology"
DOI: 10.1111/cen.14861
Abstract: Although there is growing evidence associating nonfunctioning adrenal incidentalomas (NFAI) with cardiovascular risk factors, there are limited data whether NFAI and autonomous cortisol secretion (ACS) groups have similar or different clinical and metabolic features. The… read more here.
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Published in 2025 at "Journal of the Endocrine Society"
DOI: 10.1210/jendso/bvaf136
Abstract: Abstract Context Data on diagnostic accuracy of dehydroepiandrosterone sulfate (DHEA-S) for mild autonomous cortisol secretion (MACS) and adrenal insufficiency (AI) are discrepant. Objective We conducted a systematic review and meta-analysis of published studies assessing the… read more here.
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Published in 2025 at "Journal of the Endocrine Society"
DOI: 10.1210/jendso/bvaf149.451
Abstract: Abstract Disclosure: K.F. Mendoza: None. V.E. Bravo: None. D.L. Elazegui: None. G.D. Wassmer: None. Mild autonomous cortisol secretion (MACS) is an increasingly recognized entity in a substantial number of patients with adrenal adenomas. Unlike overt… read more here.
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Published in 2020 at "European journal of endocrinology"
DOI: 10.1530/eje-20-0301
Abstract: Objective To identify radiologic features that correlate with mild autonomous cortisol excess using planar and volumetric analysis. Design Cross-sectional study. Methods In the study, 64 patients with overt Cushing syndrome (CS), 59 patients with mild… read more here.
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Published in 2022 at "European journal of endocrinology"
DOI: 10.1530/eje-21-1157
Abstract: OBJECTIVE The presence of autonomous cortisol secretion (ACS) in patients with primary aldosteronism (PA) is common and potentially associated with poor outcomes. The aim of this study was to investigate the association between autonomous cortisol… read more here.
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Published in 2022 at "European journal of endocrinology"
DOI: 10.1530/eje-22-0286
Abstract: OBJECTIVE Concurrent autonomous cortisol secretion(ACS) in patients with primary aldosteronism(PA) was reported more frequently. Several somatic mutations including PRKACA, GNAS, and CTNNB1 were identified in cortisol-producing adenomas(CPAs). The presence of these mutations in unilateral PA(uPA)… read more here.
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Published in 2024 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2024.1521680
Abstract: Objectives Glucocorticoid cosecretion is more common in primary aldosteronism (PA) than previously thought. Chronic subtle cortisol excess in patients with mild autonomous cortisol secretion (MACS) negatively affects bone health. This study aimed to evaluate the… read more here.