Rapid depletion of ESCRT protein Vps4 underlies injury-induced autophagic impediment and Wallerian degeneration
Sign Up to like & getrecommendations! Published in 2019 at "Science Advances"
DOI: 10.1126/sciadv.aav4971
Abstract: The ESCRT complex protein Vps4 is rapidly depleted upon nerve injury, causing autophagic impediment and axonal degeneration. Injured axons undergo a controlled, self-destruction process, known as Wallerian degeneration. However, the underlying mechanism remains elusive. Using… read more here.
Keywords: vps4; autophagic impediment; escrt; wallerian degeneration ... See more keywords