Autophagic protein ULK1 regulates FOXM1 signalling in human hepatoma cells.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2020.08.068
Abstract: Hepatocellular cancer (HCC) is one of the leading causes of mortality worldwide. Unfortunately, a limited choice of anti-cancer drugs is available for treatment, owing to their minimal efficacy and development of acquired resistance. Autophagy, a… read more here.
Keywords: ulk1 regulates; hcc progression; protein ulk1; autophagy ... See more keywords
Nonradioactive quantification of autophagic protein degradation with L-azidohomoalanine labeling
Sign Up to like & getrecommendations! Published in 2017 at "Nature Protocols"
DOI: 10.1038/nprot.2016.160
Abstract: At present, several assays that use radioisotope labeling to quantify the degradation of long-lived proteins have been developed to measure autophagic flux. Here, we describe a nonradioactive pulse–chase protocol using L-azidohomoalanine (AHA) labeling to quantify… read more here.
Keywords: degradation; nonradioactive quantification; quantification autophagic; protein degradation ... See more keywords
Expression and clinical significance of autophagic protein LC3B and EMT markers in gastric cancer
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Management and Research"
DOI: 10.2147/cmar.s164842
Abstract: Background and aim Gastric cancer (GC) is a fatal malignancy with high rate of recurrence and metastasis. Here, we investigated the correlations between the expression of autophagic protein LC3B and 2 epithelial–mesenchymal transition-related proteins (E-cadherin… read more here.
Keywords: vimentin; gastric cancer; expression; cancer ... See more keywords