Autophagosome Biogenesis and the Endoplasmic Reticulum: A Plant Perspective.
Sign Up to like & getrecommendations! Published in 2018 at "Trends in plant science"
DOI: 10.1016/j.tplants.2018.05.002
Abstract: The autophagosome is a double-membrane compartment formed during autophagy that sequesters and delivers cargoes for their degradation or recycling into the vacuole. Analyses of the AuTophaGy-related (ATG) proteins have unveiled dynamic mechanisms for autophagosome biogenesis.… read more here.
Keywords: autophagosome biogenesis; endoplasmic reticulum; plant; biogenesis endoplasmic ... See more keywords
Autophagosome biogenesis and human health
Sign Up to like & getrecommendations! Published in 2020 at "Cell Discovery"
DOI: 10.1038/s41421-020-0166-y
Abstract: Autophagy degrades the cytoplasmic contents engulfed by autophagosomes. Besides providing energy and building blocks during starvation via random degradation, autophagy selectively targets cytotoxic components to prevent a wide range of diseases. This preventive activity of… read more here.
Keywords: human health; autophagosome biogenesis; biogenesis human;
A new type of ERGIC–ERES membrane contact mediated by TMED9 and SEC12 is required for autophagosome biogenesis
Sign Up to like & getrecommendations! Published in 2021 at "Cell Research"
DOI: 10.1038/s41422-021-00563-0
Abstract: Under stress, the endomembrane system undergoes reorganization to support autophagosome biogenesis, which is a central step in autophagy. How the endomembrane system remodels has been poorly understood. Here we identify a new type of membrane… read more here.
Keywords: ergic eres; sec12; autophagosome biogenesis; membrane contact ... See more keywords
Initial Steps in Mammalian Autophagosome Biogenesis
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2018.00146
Abstract: During the last decade, autophagy has been pointed out as a central process in cellular homeostasis with the consequent implication in most cellular settings and human diseases pathology. At present, there is significant data available… read more here.
Keywords: initial steps; autophagosome biogenesis; mammalian autophagosome; steps mammalian ... See more keywords
Recent Advances in Membrane Shaping for Plant Autophagosome Biogenesis
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2020.00565
Abstract: Autophagy is an intracellular degradation process, which is highly conserved in eukaryotes. During this process, unwanted cytosolic constituents are sequestered and delivered into the vacuole/lysosome by a double-membrane organelle known as an autophagosome. The autophagosome… read more here.
Keywords: advances membrane; recent advances; autophagosome biogenesis; plant ... See more keywords