Upregulation of the Autophagy Adaptor p62/SQSTM1 Prolongs Health and Lifespan in Middle-Aged Drosophila.
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DOI: 10.1016/j.celrep.2019.06.070
Abstract: Autophagy, a lysosomal degradation pathway, plays crucial roles in health and disease. p62/SQSTM1 (hereafter p62) is an autophagy adaptor protein that can shuttle ubiquitinated cargo for autophagic degradation. Here, we show that upregulating the Drosophila… read more here.
Keywords: p62 sqstm1; health; p62; autophagy adaptor ... See more keywords