TNF-α regulates the early development of avascular necrosis of femoral head by mediating osteoblast autophagy and apoptosis via p38 MAPK/NF-κB signaling pathway.
Sign Up to like & getrecommendations! Published in 2020 at "Cell biology international"
DOI: 10.1002/cbin.11394
Abstract: Previous studies have shown that the tumor necrosis factor-α (TNF-α) levels in serum and bone tissues form avascular necrosis of femoral head (ANFH) patients were higher than that of normal individuals, indicating TNF-α might play… read more here.
Keywords: p38 mapk; autophagy apoptosis; tnf; apoptosis ... See more keywords
Effects of fucoxanthin on autophagy and apoptosis in SGC‐7901cells and the mechanism
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DOI: 10.1002/jcb.27022
Abstract: Autophagy and apoptosis are involved in the development of a variety of cancers. Fucoxanthin is a natural compound known to have antitumor effects, so we aimed to explore its effects on autophagy and apoptosis in… read more here.
Keywords: apoptosis sgc; autophagy apoptosis; effects fucoxanthin; apoptosis ... See more keywords
Bowman‐Birk inhibitor modifies transcription of autophagy and apoptosis genes in an in vitro model of Alzheimer's disorder
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.28391
Abstract: Alzheimer, a current neurodegenerative disorder has adverse effects on memory and behavior. β‐Amyloid peptide accumulations are the hallmarks of Alzheimer. Dysfunction of autophagy and apoptosis is detected in Alzheimer's disease. The effect of Bowman‐Birk inhibitor… read more here.
Keywords: autophagy apoptosis; model alzheimer; vitro model; birk inhibitor ... See more keywords
Silencing of microRNA‐27a facilitates autophagy and apoptosis of melanoma cells through the activation of the SYK‐dependent mTOR signaling pathway
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.29696
Abstract: Melanoma is considered as an aggressive neoplastic transformation and featured with high metastatic potential. Although some studies have provided targets for novel therapeutic interventions, clinical development of targeted drugs for melanoma still remains obscure. Therefore,… read more here.
Keywords: melanoma; autophagy apoptosis; mir 27a; apoptosis melanoma ... See more keywords
Hydroquinone-induced endoplasmic reticulum stress affects TK6 cell autophagy and apoptosis via ATF6-mTOR.
Sign Up to like & getrecommendations! Published in 2023 at "Environmental toxicology"
DOI: 10.1002/tox.23814
Abstract: Hydroquinone (HQ), one of the main active metabolites of benzene in vivo, 7is commonly used as a surrogate for benzene in in vitro studies and has been shown to be cytotoxic. The aim of this… read more here.
Keywords: endoplasmic reticulum; apoptosis; autophagy apoptosis; reticulum stress ... See more keywords
Evaluation of toxic effects induced by arsenic trioxide or/and antimony on autophagy and apoptosis in testis of adult mice
Sign Up to like & getrecommendations! Published in 2021 at "Environmental Science and Pollution Research"
DOI: 10.1007/s11356-021-14486-1
Abstract: Arsenic trioxide (ATO) and antimony (Sb) are well-known ubiquitous environmental contaminants and cause unpromising male reproductive effects in target and non-target exposed organisms. The main objective of this study was to investigate the effects of… read more here.
Keywords: autophagy apoptosis; apoptosis; antimony; group ... See more keywords
HDAC4 Knockdown Induces Preeclampsia Cell Autophagy and Apoptosis by miR-29b
Sign Up to like & getrecommendations! Published in 2020 at "Reproductive Sciences"
DOI: 10.1007/s43032-020-00286-4
Abstract: Preeclampsia (PE) is one of the main causes of maternal death and perinatal morbidity and mortality. Considering that histone deacetylase 4 (HDAC4) activity could relate to trophoblast cell motility and be antagonized by miR-29b, the… read more here.
Keywords: autophagy apoptosis; hdac4; trophoblast; mir 29b ... See more keywords
Thioredoxin domain-containing protein 9 (TXNDC9) contributes to oxaliplatin resistance through regulation of autophagy-apoptosis in colorectal adenocarcinoma.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2020.01.092
Abstract: Colorectal cancer (CRC) is the third most commonly malignancy worldwide. The incidence of CRC is on the rise and leads to indisputable society burden due to the high cost of cancer treatments. Resistance to oxaliplatin-chemotherapy… read more here.
Keywords: autophagy apoptosis; txndc9; resistance; crc ... See more keywords
Ursodeoxycholic acid alleviates nonalcoholic fatty liver disease by inhibiting apoptosis and improving autophagy via activating AMPK.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2020.05.128
Abstract: Ursodeoxycholic acid (UDCA), first identified in bear bile, was widely used in cholestatic liver diseases. Our previous studies have suggested UDCA may exert favorable influence on hepatic steatosis. However, the molecular mechanism remains elusive. Given… read more here.
Keywords: autophagy apoptosis; fatty liver; ursodeoxycholic acid; apoptosis ... See more keywords
Curcumin alleviates arsenic-induced toxicity in PC12 cells via modulating autophagy/apoptosis.
Sign Up to like & getrecommendations! Published in 2020 at "Ecotoxicology and environmental safety"
DOI: 10.1016/j.ecoenv.2020.110756
Abstract: Arsenic is a recognized highly toxic contaminant, responsible for numerous human diseases and affecting many millions of people in different parts of the world. Contrarily, curcumin is a natural dietary polyphenolic compound and the main… read more here.
Keywords: autophagy apoptosis; pc12 cells; toxicity; arsenic induced ... See more keywords
Stem-leaf saponins from Panax notoginseng counteract aberrant autophagy and apoptosis in hippocampal neurons of mice with cognitive impairment induced by sleep deprivation
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Ginseng Research"
DOI: 10.1016/j.jgr.2019.01.009
Abstract: Backgroud Sleep deprivation (SD) impairs learning and memory by inhibiting hippocampal functioning at molecular and cellular levels. Abnormal autophagy and apoptosis are closely associated with neurodegeneration in the central nervous system. This study is aimed… read more here.
Keywords: autophagy apoptosis; hippocampal neurons; sleep deprivation; apoptosis ... See more keywords