Chaperone-Mediated Autophagy Controls Proteomic and Transcriptomic Pathways to Maintain Glioma Stem Cell Activity
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DOI: 10.1158/0008-5472.can-21-2161
Abstract: A receptor of chaperone-mediated autophagy regulates glioblastoma stem cells and may serve as a potential biomarker for advanced tumor grade and poor survival in this disease. read more here.
Keywords: controls proteomic; autophagy controls; mediated autophagy; stem ... See more keywords
Autophagy controls Wolbachia infection upon bacterial damage and in aging Drosophila
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DOI: 10.3389/fcell.2022.976882
Abstract: Autophagy is a conserved catabolic process in eukaryotic cells that degrades intracellular components in lysosomes, often in an organelle-specific selective manner (mitophagy, ERphagy, etc). Cells also use autophagy as a defense mechanism, eliminating intracellular pathogens… read more here.
Keywords: wolbachia infection; damage; drosophila; wolbachia ... See more keywords
Autophagy Controls Nrf2-Mediated Dichotomy in Pressure Overloaded Hearts
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DOI: 10.3389/fphys.2021.673145
Abstract: Burgeoning evidence has indicated that normal autophagy is required for nuclear factor erythroid 2-related factor (Nrf2)-mediated cardiac protection whereas autophagy inhibition turns on Nrf2-mediated myocardial damage and dysfunction in a setting of pressure overload (PO).… read more here.
Keywords: autophagy inhibition; nrf2 mediated; autophagy; autophagy controls ... See more keywords