Dysfunctional Autophagy and Endolysosomal System in Neurodegenerative Diseases: Relevance and Therapeutic Options
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DOI: 10.3389/fncel.2020.602116
Abstract: Autophagy and endolysosomal trafficking are crucial in neuronal development, function and survival. These processes ensure efficient removal of misfolded aggregation-prone proteins and damaged organelles, such as dysfunctional mitochondria, thus allowing the maintenance of proper cellular… read more here.
Keywords: endolysosomal system; dysfunctional autophagy; system neurodegenerative; neurodegenerative diseases ... See more keywords