Prognostic score model based on six m6A‐related autophagy genes for predicting survival in esophageal squamous cell carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.24507
Abstract: Prognostic signatures based on autophagy genes have been proposed for esophageal squamous cell carcinoma (ESCC). Autophagy genes are closely associated with m6A genes. Our purpose is to identify m6A‐related autophagy genes in ESCC and develop… read more here.
Keywords: cell carcinoma; m6a related; squamous cell; autophagy genes ... See more keywords
Biological Functions of Autophagy Genes: A Disease Perspective
Sign Up to like & getrecommendations! Published in 2019 at "Cell"
DOI: 10.1016/j.cell.2018.09.048
Abstract: The lysosomal degradation pathway of autophagy plays a fundamental role in cellular, tissue, and organismal homeostasis and is mediated by evolutionarily conserved autophagy-related (ATG) genes. Definitive etiological links exist between mutations in genes that control… read more here.
Keywords: genes disease; autophagy genes; biological functions; functions autophagy ... See more keywords
Among autophagy genes, ATG16L1 but not IRGM is associated with Crohn's disease in Iranians.
Sign Up to like & getrecommendations! Published in 2018 at "Gene"
DOI: 10.1016/j.gene.2018.06.074
Abstract: BACKGROUND The prevalence of inflammatory bowel diseases is uprising in countries like Iran. Genetic predisposing elements play prominent role in the pathogenesis of Crohn's disease. In this study we studied the role of autophagy genes… read more here.
Keywords: autophagy genes; irgm associated; associated crohn; disease ... See more keywords
Myeloid autophagy genes protect mice against fatal TNF- and LPS-induced cytokine storm syndromes
Sign Up to like & getrecommendations! Published in 2022 at "Autophagy"
DOI: 10.1080/15548627.2022.2116675
Abstract: ABSTRACT Macroautophagy/autophagy regulates inflammation via multiple mechanisms, including lysosomal degradation of specific cellular components. Certain autophagy gene “cassettes” also participate in non-canonical processes to mediate important biological activities. While select autophagy genes in myeloid cells… read more here.
Keywords: storm syndromes; autophagy genes; autophagy related; cytokine storm ... See more keywords
The role of radiotherapy-related autophagy genes in the prognosis and immune infiltration in lung adenocarcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.992626
Abstract: Background There is a close relationship between radiotherapy and autophagy in tumors, but the prognostic role of radiotherapy-related autophagy genes (RRAGs) in lung adenocarcinoma (LUAD) remains unclear. Methods Data used in the current study were… read more here.
Keywords: luad; role; radiotherapy; autophagy genes ... See more keywords
EVALUATION OF ANTIOXIDANTS ENZYMES AND AUTOPHAGY GENES IN THE BLOOD OF IRAQI SMOKER VOLUNTEERS.
Sign Up to like & getrecommendations! Published in 2023 at "Wiadomosci lekarskie"
DOI: 10.36740/wlek202303106
Abstract: OBJECTIVE The aim: In this study, we investigated the expression level of LC3A, LC3B, Beclin1, and ATG5 in the blood of smokers as well as non-smokers volunteers. On the other hand, total antioxidant status (TAS),… read more here.
Keywords: smoker; autophagy genes; compared non; blood ... See more keywords