NPPA/atrial natriuretic peptide is an extracellular modulator of autophagy in the heart
Sign Up to like & getrecommendations! Published in 2022 at "Autophagy"
DOI: 10.1080/15548627.2022.2115675
Abstract: ABSTRACT NPPA/atrial natriuretic peptide (natriuretic peptide type A) exerts critical pleiotropic effects in the cardiovascular system, limiting cardiomyocyte hypertrophy and death, reducing cardiac fibrosis and promoting vascular integrity. However, the molecular mechanisms underlying these beneficial… read more here.
Keywords: natriuretic peptide; nppa atrial; atrial natriuretic; peptide ... See more keywords
The role of the Hippo pathway in autophagy in the heart.
Sign Up to like & getrecommendations! Published in 2022 at "Cardiovascular research"
DOI: 10.1093/cvr/cvac014
Abstract: The Hippo pathway, an evolutionarily conserved signaling mechanism, controls organ size and tumorigenesis. Increasing lines of evidence suggest that autophagy, an important mechanism of lysosome-mediated cellular degradation, is regulated by the Hippo pathway, which thereby… read more here.
Keywords: hippo pathway; autophagy heart; role hippo; pathway autophagy ... See more keywords
Abstract We123: Cardiomyocyte Specific Sustained Atg7 Overexpression Activates Mitochondrial Autophagy in the Heart
Sign Up to like & getrecommendations! Published in 2024 at "Circulation Research"
DOI: 10.1161/res.135.suppl_1.we123
Abstract: Introduction: Accumulating evidence indicates that autophagy-related protein 7 (Atg7) is essential in cellular autophagy. Our earlier studies showed that Atg7 is required to promote macro-autophagy in the heart. However, it is unknown if the activation… read more here.
Keywords: mice; heart; atg7; activation ... See more keywords