LPS-induced autophagy in human dental pulp cells is associated with p38.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of molecular histology"
DOI: 10.1007/s10735-021-10004-2
Abstract: Lipopolysaccharides (LPS), which are components of the cell wall of Gram-negative bacteria, are among the important factors that induce inflammation, including pulpitis. Autophagy in human dental pulp cells (hDPCs) acts as a protective mechanism that… read more here.
Keywords: autophagy human; lps induced; human dental; p38 ... See more keywords
Timosaponin AIII induces apoptosis and autophagy in human melanoma A375-S2 cells
Sign Up to like & getrecommendations! Published in 2017 at "Archives of Pharmacal Research"
DOI: 10.1007/s12272-016-0763-3
Abstract: Timosaponin AIII (AIII), a steroidal saponin isolated from Anemarrhena asphodeloides Bge. Our study showed that AIII induced both apoptosis and autophagy, and autophagy inhibited apoptosis in A375S2 cells. Furtherly, this study was carried out to… read more here.
Keywords: apoptosis autophagy; timosaponin aiii; aiii induces; autophagy human ... See more keywords
SIRT1 directly activates autophagy in human chondrocytes.
Sign Up to like & getrecommendations! Published in 2020 at "Cell death discovery"
DOI: 10.1038/s41420-020-0277-0
Abstract: Osteoarthritis (OA) is the most common form of arthritis worldwide with no effective treatment. Ageing is the primary risk factor for OA. We sought to investigate if there is a distinct and functional convergence of… read more here.
Keywords: activates autophagy; chondrocytes sirt1; directly activates; autophagy chondrocytes ... See more keywords
Role of OSGIN1 in mediating smoking-induced autophagy in the human airway epithelium
Sign Up to like & getrecommendations! Published in 2017 at "Autophagy"
DOI: 10.1080/15548627.2017.1301327
Abstract: ABSTRACT Enhanced macroautophagy/autophagy is recognized as a component of the pathogenesis of smoking-induced airway disease. Based on the knowledge that enhanced autophagy is linked to oxidative stress and the DNA damage response, both of which… read more here.
Keywords: autophagy human; smoking; small airway; smoking induced ... See more keywords
Combination of Ascorbic Acid and Menadione Induces Cytotoxic Autophagy in Human Glioblastoma Cells
Sign Up to like & getrecommendations! Published in 2022 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2022/2998132
Abstract: We investigated the ability of the ascorbic acid (AA) and menadione (MD) combination, the well-known reactive oxidative species- (ROS-) generating system, to induce autophagy in human U251 glioblastoma cells. A combination of AA and MD… read more here.
Keywords: glioblastoma; autophagy human; acid menadione; ascorbic acid ... See more keywords
The Novel Inducer of Innate Immunity HO53 Stimulates Autophagy in Human Airway Epithelial Cells
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Innate Immunity"
DOI: 10.1159/000521602
Abstract: Aroylated phenylenediamines (APDs) are novel modulators of innate immunity with respect to enhancing the expression of antimicrobial peptides and maintaining epithelial barrier integrity. Here, we present a new study on induction of autophagy in human… read more here.
Keywords: autophagy human; ho53; innate immunity; epithelial cells ... See more keywords
Nicotine regulates autophagy of human periodontal ligament cells through α7 nAchR that promotes secretion of inflammatory factors IL-1β and IL-8
Sign Up to like & getrecommendations! Published in 2021 at "BMC Oral Health"
DOI: 10.1186/s12903-021-01894-5
Abstract: Background Nicotine is an important risk factor and the main toxic component associated with periodontitis. However, the mechanism of nicotine induced periodontitis is not clear. To investigated the mechanism through which nicotine regulates autophagy of… read more here.
Keywords: regulates autophagy; nicotine; nicotine regulates; inflammatory factors ... See more keywords
Sirt3 promotes the autophagy of HK-2 human proximal tubular epithelial cells via the inhibition of Notch-1/Hes-1 signaling
Sign Up to like & getrecommendations! Published in 2021 at "Molecular Medicine Reports"
DOI: 10.3892/mmr.2021.12273
Abstract: Diabetic nephropathy (DN) is a predominant cause of end-stage renal disease. The impairment of the autophagy of human renal tubular epithelial cells (HK-2 cells) is involved in the pathogenic mechanisms of DN. Sirtuin (Sirt)3 regulates… read more here.
Keywords: notch hes; inhibition; notch; expression ... See more keywords
Capsaicin induces apoptosis and autophagy in human melanoma cells
Sign Up to like & getrecommendations! Published in 2019 at "Oncology Letters"
DOI: 10.3892/ol.2019.10206
Abstract: Melanoma is the most lethal type of skin cancer; rapid metastasis and resistance to conventional radio- and chemotherapy make melanoma the most aggressive type of skin cancer. In addition, there is a high recurrence rate… read more here.
Keywords: melanoma; melanoma cells; capsaicin induced; autophagy human ... See more keywords