Erratum to: Autophagy induction by SIRT6 is involved in oxidative stress-induced neuronal damage
Sign Up to like & getrecommendations! Published in 2017 at "Protein & Cell"
DOI: 10.1007/s13238-017-0370-1
Abstract: The authors of this article would like to request the following replacement to the section ACKNOWLEGEMENTS: We are grateful to Mrs. Jin Xu for her assistance in flow cytometry. This study is supported by the… read more here.
Keywords: induction sirt6; erratum autophagy; sirt6 involved; involved oxidative ... See more keywords
Effect of erythropoietin production induced by hypoxia on autophagy in HepG2 cells.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2017.11.167
Abstract: The induction of hypoxia inducible factor (HIF) and autophagy are important cellular responses to hypoxia. The production of erythropoietin (EPO) regulated by HIF is increased by hypoxia and participates in cell protection in various organs… read more here.
Keywords: production; epo; hypoxia; autophagy induction ... See more keywords
Autophagy induction impairs Wnt/β-catenin signalling through β-catenin relocalisation in glioblastoma cells.
Sign Up to like & getrecommendations! Published in 2019 at "Cellular signalling"
DOI: 10.1016/j.cellsig.2018.10.017
Abstract: Autophagy is an evolutionary conserved process mediating lysosomal degradation of cytoplasmic material. Its involvement in cancer progression is highly controversial, due to its dual role in both limiting tumoural transformation and in protecting established tumoral… read more here.
Keywords: catenin relocalisation; catenin; catenin signalling; autophagy induction ... See more keywords
Effect of chronic exposure to nanopolystyrene on nematode Caenorhabditis elegans.
Sign Up to like & getrecommendations! Published in 2020 at "Chemosphere"
DOI: 10.1016/j.chemosphere.2020.127172
Abstract: Nanoplastic exposure could cause toxicity to Caenorhabditis elegans at various aspects. Nevertheless, the effects of chronic exposure to nanoplastics remain largely unclear in nematodes. In this study, we employed C. elegans as an animal model to… read more here.
Keywords: exposure; caenorhabditis elegans; toxicity; autophagy induction ... See more keywords
Cytotoxicity and autophagy induction by graphene quantum dots with different functional groups.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of environmental sciences"
DOI: 10.1016/j.jes.2018.07.014
Abstract: Graphene quantum dots (GQDs) possess great potential in various applications due to their superior physicochemical properties and wide array of available surface modifications. However, the toxicity of GQDs has not been systematically assessed, thus hindered… read more here.
Keywords: graphene quantum; gqds; hgqds; autophagy induction ... See more keywords
Nicotinamide protects hepatocytes against palmitate-induced lipotoxicity via SIRT1-dependent autophagy induction.
Sign Up to like & getrecommendations! Published in 2017 at "Nutrition research"
DOI: 10.1016/j.nutres.2017.03.005
Abstract: Lipotoxicity induced by saturated fatty acids (SFAs) plays a pathological role in the development of non-alcoholic fatty liver disease (NAFLD); however, the exact mechanism remains to be clearly elucidated. Palmitate is the most abundant SFA… read more here.
Keywords: nicotinamide supplementation; autophagy induction; anti lipotoxic; palmitate induced ... See more keywords
An antibody for analysis of autophagy induction
Sign Up to like & getrecommendations! Published in 2019 at "Nature Methods"
DOI: 10.1038/s41592-019-0661-y
Abstract: Autophagy is a degradative program that maintains cellular homeostasis. Autophagy defects have been described in numerous diseases. However, analysis of autophagy rates can be challenging, particularly in rare cell populations or in vivo, due to… read more here.
Keywords: analysis autophagy; autophagy induction; antibody; phospho atg16l1 ... See more keywords
ULK1 phosphorylates Ser30 of BECN1 in association with ATG14 to stimulate autophagy induction
Sign Up to like & getrecommendations! Published in 2018 at "Autophagy"
DOI: 10.1080/15548627.2017.1422851
Abstract: ABSTRACT ULK1 (unc51-like autophagy activating kinase 1) is a serine/threonine kinase that plays a key role in regulating macroautophagy/autophagy induction in response to amino acid starvation. Despite the recent progress in understanding ULK1 functions, the… read more here.
Keywords: autophagy induction; ulk1 phosphorylates; autophagy; atg14 ... See more keywords
Enhanced viability and function of mesenchymal stromal cell spheroids is mediated via autophagy induction
Sign Up to like & getrecommendations! Published in 2020 at "Autophagy"
DOI: 10.1080/15548627.2020.1850608
Abstract: ABSTRACT Mesenchymal stromal cells (MSCs) have received attention as promising therapeutic agents for the treatment of various diseases. However, poor post-transplantation viability is a major hurdle in MSC-based therapy, despite encouraging results in many inflammatory… read more here.
Keywords: mesenchymal stromal; viability; ros production; autophagy induction ... See more keywords
ULK3-dependent activation of GLI1 promotes DNMT3A expression upon autophagy induction
Sign Up to like & getrecommendations! Published in 2022 at "Autophagy"
DOI: 10.1080/15548627.2022.2039993
Abstract: ABSTRACT Macroautophagy/autophagy is a tightly regulated catabolic process, which contributes at baseline level to cellular homeostasis, and upon its stimulation to the adaptive cellular response to intra- and extracellular stress stimuli. Decrease of autophagy activity… read more here.
Keywords: upon autophagy; gli1; expression; dependent activation ... See more keywords
Autophagy induction sensitizes cancer cells to anti-cancer drugs.
Sign Up to like & getrecommendations! Published in 2022 at "Autophagy"
DOI: 10.1080/15548627.2022.2162703
Abstract: Resistance to anti-cancer therapy is a major challenge for cancer treatment. Many studies revealed that macroautophagy/autophagy inhibition can overcome autophagy-mediated therapy resistance, but these efforts have not yet led to the success of clinical applications.… read more here.
Keywords: cancer; anti cancer; cancer drugs; autophagy induction ... See more keywords