The emerging roles of autophagy in intestinal epithelial cells and its links to inflammatory bowel disease
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DOI: 10.1042/bst20221300
Abstract: Landmark genome-wide association studies (GWAS) identified that mutations in autophagy genes correlated with inflammatory bowel disease (IBD), a heterogenous disease characterised by prolonged inflammation of the gastrointestinal tract, that can reduce a person's quality of… read more here.
Keywords: autophagy intestinal; inflammatory bowel; bowel disease; autophagy ... See more keywords
Shear stress induces noncanonical autophagy in intestinal epithelial monolayers
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DOI: 10.1091/mbc.e17-01-0021
Abstract: Shear stress applied on the apical side of polarizing intestinal cells induces vacuole formation via the autophagy machinery. This response is relayed through apical microvilli that act as mechanosensors linking the physical environment to the… read more here.
Keywords: induces noncanonical; intestinal epithelial; autophagy intestinal; shear stress ... See more keywords