Lipid droplets and lipotoxicity during autophagy
Sign Up to like & getrecommendations! Published in 2017 at "Autophagy"
DOI: 10.1080/15548627.2017.1359451
Abstract: ABSTRACT Lipid droplets (LDs) are neutral lipid storage organelles that provide a rapidly accessible source of fatty acids (FAs) for energy during periods of nutrient deprivation. Surprisingly, lipids released by the macroautophagic/autophagic breakdown of membranous… read more here.
Keywords: droplets lipotoxicity; lipid droplets; autophagy lipid; lipotoxicity autophagy ... See more keywords
GANT61 Modulates Autophagy and Lipid Metabolism in Ovarian Cancer
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DOI: 10.1111/cpr.70051
Abstract: GANT61 induced autophagy via the AKT pathway and promoted the accumulation of lipid droplets in both cell lines. The molecular mechanism behind this lipid accumulation appears to involve the mediation of SREBP1. Furthermore, the combination… read more here.
Keywords: lipid metabolism; autophagy lipid; metabolism ovarian; modulates autophagy ... See more keywords
Regulation of autophagy and lipid accumulation under phosphate limitation in Rhodotorula toruloides
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2022.1046114
Abstract: Background It is known that autophagy is essential for cell survival under stress conditions. Inorganic phosphate (Pi) is an essential nutrient for cell growth and Pi-limitation can trigger autophagy and lipid accumulation in oleaginous yeasts,… read more here.
Keywords: autophagy lipid; limitation; rhodotorula toruloides; lipid accumulation ... See more keywords