Autophagy in Neurodegeneration: Can't Digest It, Spit It Out!
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DOI: 10.1016/j.tcb.2018.01.001
Abstract: The autophagy-lysosome pathway maintains cellular homeostasis and protects against neurodegenerative disorders. Recent findings show that autophagy can be impaired in these diseases, and that the cell activates an alternative Golgi-mediated degradation pathway, leading to expulsion… read more here.
Keywords: digest spit; biology; autophagy neurodegeneration; neurodegeneration digest ... See more keywords
Defects of Nutrient Signaling and Autophagy in Neurodegeneration
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.836196
Abstract: Neurons are post-mitotic cells that allocate huge amounts of energy to the synthesis of new organelles and molecules, neurotransmission and to the maintenance of redox homeostasis. In neurons, autophagy is not only crucial to ensure… read more here.
Keywords: defects nutrient; nutrient signaling; energy; signaling autophagy ... See more keywords