Regulation of Autophagy in Neurodegenerative Diseases by Natural Products.
Sign Up to like & getrecommendations! Published in 2020 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-981-15-4272-5_54
Abstract: Neurodegenerative diseases mainly include Alzheimer's disease (AD), Parkinson's disease (PD), Huntington's disease (HD). It is now found that these diseases may be related to autophagic dysfunction. The mechanism is due to abnormalities in autophagy, which… read more here.
Keywords: natural products; regulation autophagy; autophagy neurodegenerative; neurodegenerative diseases ... See more keywords
Drosophila melanogaster as a model to study autophagy in neurodegenerative diseases induced by proteinopathies
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Neuroscience"
DOI: 10.3389/fnins.2023.1082047
Abstract: Proteinopathies are a large group of neurodegenerative diseases caused by both genetic and sporadic mutations in particular genes which can lead to alterations of the protein structure and to the formation of aggregates, especially toxic… read more here.
Keywords: neurodegenerative diseases; study autophagy; model study; autophagy neurodegenerative ... See more keywords
Autophagy in Neurodegenerative Diseases: A Hunter for Aggregates
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms21093369
Abstract: Cells have developed elaborate quality-control mechanisms for proteins and organelles to maintain cellular homeostasis. Such quality-control mechanisms are maintained by conformational folding via molecular chaperones and by degradation through the ubiquitin-proteasome or autophagy-lysosome system. Accumulating… read more here.
Keywords: autophagy neurodegenerative; disease; neurodegenerative diseases; diseases hunter ... See more keywords
Therapeutic implication of autophagy in neurodegenerative diseases
Sign Up to like & getrecommendations! Published in 2017 at "BMB Reports"
DOI: 10.5483/bmbrep.2017.50.7.069
Abstract: Autophagy, a catabolic process necessary for the maintenance of intracellular homeostasis, has recently been the focus of numerous human diseases and conditions, such as aging, cancer, development, immunity, longevity, and neurodegeneration. However, the continued presence… read more here.
Keywords: therapeutic implication; implication autophagy; neurodegenerative diseases; autophagy neurodegenerative ... See more keywords