New Insights Into the Interplay Among Autophagy, the NLRP3 Inflammasome and Inflammation in Adipose Tissue
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2022.739882
Abstract: Obesity is a feature of metabolic syndrome with chronic inflammation in obese subjects, characterized by adipose tissue (AT) expansion, proinflammatory factor overexpression, and macrophage infiltration. Autophagy modulates inflammation in the enlargement of AT as an… read more here.
Keywords: inflammasome inflammation; autophagy nlrp3; adipose tissue; obesity ... See more keywords
Interaction between autophagy and the NLRP3 inflammasome in Alzheimer’s and Parkinson’s disease
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Aging Neuroscience"
DOI: 10.3389/fnagi.2022.1018848
Abstract: Autophagy degrades phagocytosed damaged organelles, misfolded proteins, and various pathogens through lysosomes as an essential way to maintain cellular homeostasis. Autophagy is a tightly regulated cellular self-degradation process that plays a crucial role in maintaining… read more here.
Keywords: autophagy nlrp3; disease; nlrp3 inflammasome; interaction autophagy ... See more keywords
The Complex Interplay between Autophagy and NLRP3 Inflammasome in Renal Diseases
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms222312766
Abstract: Autophagy is a highly conserved process of the eukaryotic cell cycle. It plays an important role in the survival and maintenance of cells by degrading organelles, proteins, and macromolecules in the cytoplasm and the circulation… read more here.
Keywords: autophagy nlrp3; interplay autophagy; nlrp3 inflammasome; renal diseases ... See more keywords
Saikosaponin A alleviates rat liver fibrosis by inhibiting Hedgehog signaling pathway-mediated autophagy and NLRP3 inflammasome
Sign Up to like & getrecommendations! Published in 2023 at "Tropical Journal of Pharmaceutical Research"
DOI: 10.4314/tjpr.v22i4.5
Abstract: Purpose: To investigate the effect of saikosaponin A (SSa) on liver fibrosis, and the underlying mechanism of action. Methods: Sprague-Dawley (SD) rats were treated with carbon tetrachloride (CCl4) in an in vivo model of liver… read more here.
Keywords: hedgehog signaling; liver fibrosis; signaling pathway; autophagy nlrp3 ... See more keywords