Vitamin D protects against particles‐caused lung injury through induction of autophagy in an Nrf2‐dependent manner
Sign Up to like & getrecommendations! Published in 2019 at "Environmental Toxicology"
DOI: 10.1002/tox.22726
Abstract: Fine particulate matter is a well‐known air pollutant threatening public health. Studies have confirmed long‐term exposure to the particles could decrease the pulmonary function, induce asthma exacerbation, and chronic obstructive pulmonary disease, as well as… read more here.
Keywords: nrf2 dependent; autophagy nrf2; induced pulmonary; induction autophagy ... See more keywords
Neuropeptide Y Promotes Human M2 Macrophage Polarization and Enhances p62/SQSTM1-Dependent Autophagy and NRF2 Activation
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232113009
Abstract: Neuropeptide Y (NPY) is an abundantly expressed peptide capable of modulating innate and adaptive immune responses and regulating chemotaxis and cytokine secretion by macrophages. Abnormal regulation of NPY is involved in the development of atherosclerosis.… read more here.
Keywords: p62 sqstm1; sqstm1 dependent; autophagy nrf2; macrophage ... See more keywords
Combined inhibition of autophagy and Nrf2 signaling augments bortezomib-induced apoptosis by increasing ROS production and ER stress in pancreatic cancer cells
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Biological Sciences"
DOI: 10.7150/ijbs.26776
Abstract: Pancreatic cancer (PC) is highly resistant to current therapies; thus, there is an urgent need to develop new treatment strategies. The proteasome is crucially important for proteostasis, which is involved in cell proliferation and survival,… read more here.
Keywords: autophagy nrf2; induced apoptosis; nrf2 signaling; autophagy ... See more keywords