High glucose downregulates the effects of autophagy on osteoclastogenesis via the AMPK/mTOR/ULK1 pathway.
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DOI: 10.1016/j.bbrc.2018.04.052
Abstract: Diabetes is a chronic disease that disrupts the balance between bone formation and bone desorption, which can lead to osteoporosis, increasing the risk of fracture. However, compared with osteoblasts, the biological effects of hyperglycemia on… read more here.
Keywords: mtor ulk1; microscopy; ampk mtor; autophagy osteoclastogenesis ... See more keywords