LncRNA SNHG12 improves cerebral ischemic-reperfusion injury by activating SIRT1/FOXO3a pathway through inhibition of autophagy and oxidative stress.
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DOI: 10.2174/1567202617666200727142019
Abstract: BACKGROUND Ischemia/reperfusion (I/R) injury involves complex biological processes and molecular mechanisms such as autophagy. Oxidative stress plays a critical role in the pathogenesis of I/R injury. LncRNAs are the regulatory factor of cerebral I/R injury.… read more here.
Keywords: sirt1 foxo3a; oxidative stress; autophagy oxidative; injury ... See more keywords