Mitofusin2 Induces Cell Autophagy of Pancreatic Cancer through Inhibiting the PI3K/Akt/mTOR Signaling Pathway
Sign Up to like & getrecommendations! Published in 2018 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2018/2798070
Abstract: Aim Pancreatic cancer is one of the most quickly fatal cancers around the world. Burgeoning researches have begun to prove that mitochondria play a crucial role in cancer treatment. Mitofusin2 (Mfn2) plays an indispensable role… read more here.
Keywords: pancreatic cancer; pi3k akt; cancer; autophagy pancreatic ... See more keywords
The Role and Mechanism of Autophagy in Pancreatic Cancer: An Update Review
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DOI: 10.2147/cmar.s328786
Abstract: Abstract Pancreatic cancer, with high morbidity and mortality rates, is one of the most malignant tumors worldwide. Despite extensive research, the prognosis remains poor. Autophagy, a lysosomal-mediated, highly conserved degradation process that removes abnormal proteins… read more here.
Keywords: mechanism autophagy; pancreatic cancer; cancer; autophagy pancreatic ... See more keywords
Molecular Pathways Controlling Autophagy in Pancreatic Cancer
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DOI: 10.3389/fonc.2017.00028
Abstract: Pancreatic ductal adenocarcinoma (PDAC) is one of the few cancer types where the 5-year survival rate shows no improvement. Despite conflicting evidence, the majority of data points to an essential role for autophagy in PDAC… read more here.
Keywords: pdac; controlling autophagy; pathways controlling; cancer ... See more keywords
Targeting autophagy in pancreatic cancer: The cancer stem cell perspective
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.1049436
Abstract: Pancreatic cancer is currently the seventh leading cause of cancer-related deaths worldwide, with the estimated death toll approaching half a million annually. Pancreatic ductal adenocarcinoma (PDAC) is the most common (>90% of cases) and most… read more here.
Keywords: pancreatic cancer; cancer stem; targeting autophagy; autophagy pancreatic ... See more keywords
The global research and emerging trends in autophagy of pancreatic cancer: A bibliometric and visualized study
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DOI: 10.3389/fonc.2022.987026
Abstract: Objective To present the global research features and hotspots, and forecast the emerging trends by conducting a bibliometric analysis based on literature related to autophagy of pancreatic cancer from 2011 to 2022. Methods The literature… read more here.
Keywords: pancreatic cancer; autophagy pancreatic; global research; emerging trends ... See more keywords
Noncoding RNAs as key modulators of autophagy in pancreatic cancer (Review).
Sign Up to like & getrecommendations! Published in 2021 at "Oncology reports"
DOI: 10.3892/or.2021.8079
Abstract: Inability of early detection as well as lack of proper therapeutic intervention, both add to the complexity of pancreatic cancer. Understanding of the basic cellular processes is of the utmost importance and autophagy is one… read more here.
Keywords: rnas key; pancreatic cancer; noncoding rnas; cancer ... See more keywords