mTOR signaling regulates Zika virus replication bidirectionally through autophagy and protein translation
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Medical Virology"
DOI: 10.1002/jmv.28422
Abstract: Zika virus (ZIKV) reemerged in 2016 and attracted much more attention worldwide. To date, the limited knowledge of ZIKV interactions with host cells in the early stages of infection impedes the prevention of viral epidemics… read more here.
Keywords: protein translation; mtor signaling; autophagy protein; zikv ... See more keywords
Autophagy and protein secretion.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of molecular biology"
DOI: 10.1016/j.jmb.2020.01.015
Abstract: Autophagy - conventional for macroautophagy - is a major recycling strategy that ensures cellular homeostasis through the selective engulfment of cytoplasmic supramolecular cargos in double membrane vesicles and their rapid dispatch to the lysosome for… read more here.
Keywords: autophagy protein; secretion; secretory; protein secretion ... See more keywords
When the autophagy protein ATG16L1 met the ciliary protein IFT20
Sign Up to like & getrecommendations! Published in 2021 at "Autophagy"
DOI: 10.1080/15548627.2021.1935004
Abstract: ABSTRACT The primary cilium (PC), a plasma membrane microtubule-based structure, is a sensor of extracellular chemical and mechanical stress stimuli. Upon ciliogenesis, the autophagy protein ATG16L1 and the ciliary protein IFT20 are co-transported to the… read more here.
Keywords: protein; ift20; autophagy protein; ciliary protein ... See more keywords
Chemotactic cell migration: the core autophagy protein ATG9A is at the leading edge.
Sign Up to like & getrecommendations! Published in 2022 at "Autophagy"
DOI: 10.1080/15548627.2022.2069903
Abstract: Accumulating data indicate that several components of the macroautophagy/autophagy machinery mediate additional functions, which do not depend on autophagosome biogenesis or lysosomal cargo degradation. In this context, we found that the core autophagy protein ATG9A… read more here.
Keywords: core autophagy; autophagy protein; leading edge; cell ... See more keywords
The Autophagy Protein ATG16L1 Is Required for Sindbis Virus-Induced eIF2α Phosphorylation and Stress Granule Formation
Sign Up to like & getrecommendations! Published in 2019 at "Viruses"
DOI: 10.3390/v12010039
Abstract: Sindbis virus (SINV) infection induces eIF2α phosphorylation, which leads to stress granule (SG) assembly. SINV infection also stimulates autophagy, which has an important role in controlling the innate immune response. The importance of autophagy to… read more here.
Keywords: phosphorylation; autophagy protein; protein atg16l1; eif2 phosphorylation ... See more keywords
Inhibition of autophagy protein LC3A as a therapeutic target in ovarian clear cell carcinomas
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Gynecologic Oncology"
DOI: 10.3802/jgo.2017.28.e33
Abstract: Objective Ovarian clear cell carcinoma (CCC) is one of histological subtypes showing poor prognosis due to chemoresistance. The association of autophagy-related proteins and clinical implementation in CCC has not been determined. Methods The present study… read more here.
Keywords: protein; autophagy protein; inhibition autophagy; expression ... See more keywords