Autophagy Receptors and Neurodegenerative Diseases.
Sign Up to like & getrecommendations! Published in 2017 at "Trends in cell biology"
DOI: 10.1016/j.tcb.2017.01.001
Abstract: Previously thought of as a nonselective digestion process, autophagy is now known to specifically degrade aggregated proteins and damaged cellular organelles through the action of autophagy receptors, which provides cellular quality control and maintains homeostasis.… read more here.
Keywords: neurodegenerative diseases; physiology; biology; receptors neurodegenerative ... See more keywords
Selective Autophagy Receptors in Antiviral Defense.
Sign Up to like & getrecommendations! Published in 2021 at "Trends in microbiology"
DOI: 10.1016/j.tim.2021.02.006
Abstract: Autophagy ensures the degradation of cytosolic substrates by the lysosomal pathway. Cargoes destined to be eliminated are confined within double-membrane vesicles called autophagosomes, prior to fusion with endolysosomal vacuoles. Autophagy receptors selectively interact with cargoes… read more here.
Keywords: selective autophagy; antiviral defense; autophagy; autophagy receptors ... See more keywords
Phosphorylation regulates the binding of autophagy receptors to FIP200 Claw domain for selective autophagy initiation
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DOI: 10.1038/s41467-021-21874-1
Abstract: The ULK complex initiates the autophagosome formation, and has recently been implicated in selective autophagy by interacting with autophagy receptors through its FIP200 subunit. However, the structural mechanism underlying the interactions of autophagy receptors with… read more here.
Keywords: fip200 claw; receptors fip200; selective autophagy; autophagy receptors ... See more keywords
Ubiquitin-coated nanodiamonds bind to autophagy receptors for entry into the selective autophagy pathway
Sign Up to like & getrecommendations! Published in 2017 at "Autophagy"
DOI: 10.1080/15548627.2016.1254864
Abstract: ABSTRACT Selective macroautophagy/autophagy plays a pivotal role in the processing of foreign pathogens and cellular components to maintain homeostasis in human cells. To date, numerous studies have demonstrated the uptake of nanoparticles by cells, but… read more here.
Keywords: selective autophagy; autophagy pathway; bind autophagy; autophagy ... See more keywords