Autophagy regulates differentiation of ovarian granulosa cells through degradation of WT1
Sign Up to like & getrecommendations! Published in 2022 at "Autophagy"
DOI: 10.1080/15548627.2021.2005415
Abstract: ABSTRACT Ovarian granulosa cells (GCs) proliferate and differentiate along with follicular growth, and this is indispensable for oocyte development and female fertility. Although the role of macroautophagy/autophagy in ovarian function has been reported, its contribution… read more here.
Keywords: autophagy regulates; ovarian granulosa; granulosa; granulosa cells ... See more keywords
Verteporfin disrupts multiple steps of autophagy and regulates p53 to sensitize osteosarcoma cells
Sign Up to like & getrecommendations! Published in 2021 at "Cancer Cell International"
DOI: 10.1186/s12935-020-01720-y
Abstract: Background Osteosarcoma (OS) is a malignant tumor of the bone mostly observed in children and adolescents. The current treatment approach includes neoadjuvant and adjuvant chemotherapy; however, drug resistance often hinders therapy in OS patients. Also,… read more here.
Keywords: protein; multiple steps; steps autophagy; disrupts multiple ... See more keywords
Autophagy regulates inflammation in intracerebral hemorrhage: Enemy or friend?
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Cellular Neuroscience"
DOI: 10.3389/fncel.2022.1036313
Abstract: Intracerebral hemorrhage (ICH) is the second-largest stroke subtype and has a high mortality and disability rate. Secondary brain injury (SBI) is delayed after ICH. The main contributors to SBI are inflammation, oxidative stress, and excitotoxicity.… read more here.
Keywords: inflammation; regulates inflammation; autophagy regulates; intracerebral hemorrhage ... See more keywords