An autophagy‐related long non‐coding RNA signature for glioma
Sign Up to like & getrecommendations! Published in 2019 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.12601
Abstract: Glioma is one of the most common types of malignant primary central nervous system tumor, and prognosis for this disease is poor. As autophagic drugs have been reported to induce glioma cell death, we investigated… read more here.
Keywords: autophagy related; risk; glioma; as1 ... See more keywords
Autophagy-related gene PXN as a prognostic marker: Promotion of ovarian cancer progression by suppressing the p110β/Vps34/Beclin1 pathway.
Sign Up to like & getrecommendations! Published in 2023 at "Cell biochemistry and function"
DOI: 10.1002/cbf.3815
Abstract: Among gynecological malignancies, ovarian cancer has the highest mortality rate and has sparked widespread interest in studying the mechanisms underlying ovarian cancer development. Based on TCGA and GEO databases, we investigated the highly expressed autophagy-related… read more here.
Keywords: ovarian cancer; expression; beclin1; autophagy related ... See more keywords
C. elegans to model autophagy-related human disorders.
Sign Up to like & getrecommendations! Published in 2020 at "Progress in molecular biology and translational science"
DOI: 10.1016/bs.pmbts.2020.01.007
Abstract: Autophagy is a highly conserved degradation process that clears damaged intracellular macromolecules and organelles in order to maintain cellular health. Dysfunctional autophagy is fundamentally linked to the development of various human disorders and pathologies. The… read more here.
Keywords: model autophagy; human disorders; related human; elegans model ... See more keywords
Abundances of autophagy-related protein LC3B in granulosa cells, cumulus cells, and oocytes during atresia of pig antral follicles.
Sign Up to like & getrecommendations! Published in 2019 at "Animal reproduction science"
DOI: 10.1016/j.anireprosci.2019.106225
Abstract: In mammals, apoptosis has been accepted as the type of programmed cell death (PCD) that occurs in ovarian follicles undergoing atresia. Results of recent studies, however, indicate autophagy may be an alternative mechanism involved in… read more here.
Keywords: protein; granulosa cells; atretic follicles; autophagy related ... See more keywords
Heterogeneous nuclear ribonucleoprotein A1 promotes the expression of autophagy-related protein 6 in human colorectal cancer.
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2019.03.179
Abstract: Autophagy, a lysosomal self-degradative process of cellular components, is essential for cellular homeostasis to response cellular stress and is tightly controlled by autophagy-related genes (ATGs). Autophagy-related gene 6 (ATG6, also known as Beclin-1 in human)… read more here.
Keywords: nuclear ribonucleoprotein; promotes expression; expression; autophagy related ... See more keywords
Parkin is downregulated among autophagy-related proteins prior to hyperphosphorylation of Tau in TS65DN mice.
Sign Up to like & getrecommendations! Published in 2021 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2021.05.016
Abstract: Autophagy is a pathway through which cells execute a plethora of functions, such as macromolecules and organelles quality control, recycling of building blocks and apoptosis. Numerous studies have shown in the past that autophagy is… read more here.
Keywords: related proteins; hyperphosphorylation tau; ts65dn mice; autophagy related ... See more keywords
Autophagy-related protein expression was associated with BRAF V600E mutation in epilepsy associated glioneuronal tumors
Sign Up to like & getrecommendations! Published in 2017 at "Epilepsy Research"
DOI: 10.1016/j.eplepsyres.2017.06.006
Abstract: PURPOSE The aim of this study was to explore the expression level of autophagy-related proteins in epileptic patients with glioneuronal tumors (GNTs) and evaluate the association with clinicopathological features. MATERIALS AND METHODS We obtained the… read more here.
Keywords: braf v600e; expression; v600e mutation; autophagy related ... See more keywords
Roles of autophagy-related genes in conidiogenesis and blastospore formation, virulence, and stress response of Beauveria bassiana.
Sign Up to like & getrecommendations! Published in 2020 at "Fungal biology"
DOI: 10.1016/j.funbio.2020.10.002
Abstract: Autophagy is a conserved intracellular recycling mechanism, in which autophagy-related genes 12 and 16 (ATG12 and ATG16) function in a complex controlling the ubiquitin-like conjugation system. In the insect-pathogenic fungus Beauveria bassiana, ATG12 and ATG16… read more here.
Keywords: virulence; stress; bbatg16; related genes ... See more keywords
Different training intensities induced autophagy and histopathology appearances potentially associated with lipid metabolism in wistar rat liver
Sign Up to like & getrecommendations! Published in 2020 at "Heliyon"
DOI: 10.1016/j.heliyon.2020.e03874
Abstract: Introduction Aerobic training has a beneficial effect on enhancing liver functions. Autophagy might potentially play a role in preventing excessive lipid accumulation, regulating oxidative stress, and inflammation in the liver. Objective To investigate the potential… read more here.
Keywords: related gene; gene expressions; histopathology; autophagy related ... See more keywords
Dynamic expression of autophagy-related factors in autoimmune encephalomyelitis and exploration of curcumin therapy
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Neuroimmunology"
DOI: 10.1016/j.jneuroim.2019.577067
Abstract: Curcumin has been used in the study of central nervous system immune-related diseases and exerts a substantial neuroprotective effect. However, the mechanism remains unclear. The AKT/mTOR autophagy-related signalling pathway plays an important role in tumour… read more here.
Keywords: signalling pathway; autoimmune encephalomyelitis; mice; autophagy related ... See more keywords
Dopamine neuron loss by selective deletion of autophagy-related gene 5 is not exacerbated by MPTP toxicity in midbrain
Sign Up to like & getrecommendations! Published in 2018 at "Neuroscience Letters"
DOI: 10.1016/j.neulet.2017.11.037
Abstract: Parkinson's disease (PD) is a progressive neurological disease, one of the pathological characteristics is a gradual loss of midbrain dopaminergic (mDA) neurons in the substantia nigra pars compacta (SNpc). In animals, PD-like symptoms can be… read more here.
Keywords: related gene; mda neurons; autophagy related; deletion autophagy ... See more keywords