Cell Apoptosis and Autophagy in Renal Fibrosis.
Sign Up to like & getrecommendations! Published in 2019 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-981-13-8871-2_28
Abstract: Renal fibrosis is the final common pathway of all chronic kidney diseases progressing to end-stage renal diseases. Autophagy, a highly conserved lysosomal degradation pathway, plays important roles in maintaining cellular homeostasis in all major types… read more here.
Keywords: fibrosis; kidney diseases; cell apoptosis; renal fibrosis ... See more keywords
Di-n-butyl phthalate exposure induced abnormal autophagy in renal tubular cells via hedgehog signaling in newborn rats.
Sign Up to like & getrecommendations! Published in 2020 at "Chemico-biological interactions"
DOI: 10.1016/j.cbi.2020.109189
Abstract: Di-n-butyl phthalate (DBP) is a pollutant that is widely present in the environment. We have previously demonstrated that maternal exposure to DBP resulted in renal fibrosis in offspring, but the underlying mechanism was not well… read more here.
Keywords: hedgehog signaling; exposure; tubular cells; renal tubular ... See more keywords
Autophagy and Renal Fibrosis
Sign Up to like & getrecommendations! Published in 2022 at "Aging and Disease"
DOI: 10.14336/ad.2021.1027
Abstract: Renal fibrosis is a common process of almost all the chronic kidney diseases progressing to end-stage kidney disease. As a highly conserved lysosomal protein degradation pathway, autophagy is responsible for degrading protein aggregates, damaged organelles,… read more here.
Keywords: renal fibrosis; fibrosis; autophagy renal;
Autophagy in renal fibrosis: Protection or promotion?
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.963920
Abstract: Autophagy is a process that degrades endogenous cellular protein aggregates and damaged organelles via the lysosomal pathway to maintain cellular homeostasis and energy production. Baseline autophagy in the kidney, which serves as a quality control… read more here.
Keywords: fibrosis protection; renal fibrosis; autophagy renal; protection promotion ... See more keywords
Short-Chain Fatty Acids Attenuate Renal Fibrosis and Enhance Autophagy of Renal Tubular Cells in Diabetic Mice Through the HDAC2/ULK1 Axis
Sign Up to like & getrecommendations! Published in 2022 at "Endocrinology and Metabolism"
DOI: 10.3803/enm.2021.1336
Abstract: Background This study investigated the effect of short-chain fatty acids (SCFAs) on diabetes in a mouse model. Methods Autophagy in Akita mice and streptozocin (STZ)-induced diabetic C57BL/6 mice was determined by Western blots and immunohistochemistry… read more here.
Keywords: renal fibrosis; diabetic mice; autophagy renal; hdac2 ... See more keywords