The HDAC6 inhibitor C1A modulates autophagy substrates in diverse cancer cells and induces cell death
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DOI: 10.1038/s41416-018-0232-5
Abstract: BackgroundCytosolic deacetylase histone deacetylase 6 (HDAC6) is involved in the autophagy degradation pathway of malformed proteins, an important survival mechanism in cancer cells. We evaluated modulation of autophagy-related proteins and cell death by the HDAC6-selective inhibitor… read more here.
Keywords: autophagy substrates; c1a; cancer; cell death ... See more keywords