The role of antioxidants in restoring MAPK 14 and a DNA damage marker level following autophagy suppression
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DOI: 10.1098/rsob.200253
Abstract: Autophagy is a lysosomal degradation mechanism for elimination and recycling of damaged intracellular organelles and proteins. Recent studies have shown that autophagy could help reduce oxidative stress by removing oxidized proteins and damaged mitochondria. Autophagy… read more here.
Keywords: dna damage; suppression; autophagy suppression; oxidative stress ... See more keywords
PAFR selectively mediates radioresistance and irradiation-induced autophagy suppression in prostate cancer cells
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.14647
Abstract: Platelet-activating factor receptor (PAFR) promotes tumorigenesis, angiogenesis and metastasis. Here, we defined the PAFR as a yielding new inhibiting target to selectively enhance the sensitivity of prostate cancer (PCa) cells to radiation. The selective responding… read more here.
Keywords: autophagy suppression; prostate cancer; pafr;