Articles with "autophagy thymic" as a keyword



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Redox status regulates autophagy in thymic stromal cells and promotes T cell tolerance

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Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"

DOI: 10.1073/pnas.2204296119

Abstract: Significance Thymic stromal cells impose T cell self-tolerance by presenting self-antigens to developing T cells and inducing apoptosis in strongly self-reactive cells, a process known as clonal deletion. Self-antigen presentation is facilitated by particularly high… read more here.

Keywords: cells promotes; autophagy thymic; tolerance; thymic stromal ... See more keywords