Design of modular autoproteolytic gene switches responsive to anti-coronavirus drug candidates.
Sign Up to like & getrecommendations! Published in 2021 at "Nature communications"
DOI: 10.1038/s41467-021-27072-3
Abstract: The main (Mpro) and papain-like (PLpro) proteases encoded by SARS-CoV-2 are essential to process viral polyproteins into functional units, thus representing key targets for anti-viral drug development. There is a need for an efficient inhibitor… read more here.
Keywords: design modular; autoproteolytic gene; drug candidates; drug ... See more keywords