Bias induced by ignoring double truncation inherent in autopsy-confirmed survival studies of neurodegenerative diseases.
Sign Up to like & getrecommendations! Published in 2019 at "Statistics in medicine"
DOI: 10.1002/sim.8185
Abstract: Neurodegenerative diseases require an autopsy for confirmation of diagnosis. When death is the event of interest, studies based on autopsy-confirmed diagnoses result in right truncated survival times because individuals who live past the end of… read more here.
Keywords: autopsy confirmed; neurodegenerative diseases; double truncation; studies neurodegenerative ... See more keywords
Autopsy-confirmed fulminant mucormycosis: a skin lesion revealing multiple organ dissemination
Sign Up to like & getrecommendations! Published in 2018 at "Intensive Care Medicine"
DOI: 10.1007/s00134-018-5331-5
Abstract: A 54-year-old man was admitted to the intensive care unit (ICU) with a coma requiring mechanical ventilation (day 1). The Glasgow coma score was 3 and there was no meningeal syndrome. A single inflammatory and… read more here.
Keywords: autopsy confirmed; skin lesion; day; multiple organ ... See more keywords
A-1 Neuropsychiatric Symptoms over Time in Autopsy-Confirmed Alzheimer’s Disease, Lewy Body Disease, and Mixed Pathology
Sign Up to like & getrecommendations! Published in 2021 at "Archives of Clinical Neuropsychology"
DOI: 10.1093/arclin/acab062.02
Abstract: Neuropsychiatric symptoms (NPS) are common in neurodegenerative disease, but longitudinal studies using large autopsy-confirmed samples are lacking. Our primary aim was to investigate progression of NPS over time in autopsy-confirmed Alzheimer’s disease (ad), Lewy body… read more here.
Keywords: lbd; autopsy confirmed; time; disease ... See more keywords
Cause of death in autopsy‐confirmed dementia disorders
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DOI: 10.1111/ene.14450
Abstract: Dementia disorders predispose for lethal complications and decrease life expectancy. A more profound knowledge regarding end‐stage conditions in dementia could therefore ameliorate treatment and care of these patients. read more here.
Keywords: confirmed dementia; autopsy confirmed; cause death; death autopsy ... See more keywords
Trajectories of Cognitive Decline in Brain Donors With Autopsy-Confirmed Alzheimer Disease and Cerebrovascular Disease
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DOI: 10.1212/wnl.0000000000200304
Abstract: Background and Objectives Cerebrovascular disease (CBVD) is frequently comorbid with autopsy-confirmed Alzheimer disease (AD), but its contribution to the clinical presentation of AD remains unclear. We leveraged the National Alzheimer's Coordinating Center (NACC) uniform and… read more here.
Keywords: autopsy confirmed; cbvd; disease; alzheimer disease ... See more keywords