Application of modern autoradiography to nuclear forensic analysis.
Sign Up to like & getrecommendations! Published in 2018 at "Forensic science international"
DOI: 10.1016/j.forsciint.2018.03.027
Abstract: Modern autoradiography techniques based on phosphorimaging technology using image plates (IPs) and digital scanning can identify heterogeneities in activity distributions and reveal material properties, serving to inform subsequent analyses. Here, we have adopted these advantages… read more here.
Keywords: nuclear forensic; sample; image; analysis ... See more keywords
Sapap3 deletion causes dynamic synaptic density abnormalities: a longitudinal [11C]UCB-J PET study in a model of obsessive–compulsive disorder-like behaviour
Sign Up to like & getrecommendations! Published in 2020 at "EJNMMI Research"
DOI: 10.1186/s13550-020-00721-2
Abstract: Background Currently, the evidence on synaptic abnormalities in neuropsychiatric disorders—including obsessive–compulsive disorder (OCD)—is emerging. The newly established positron emission tomography (PET) ligand ((R)-1-((3-((11)C-methyl-(11)C)pyridin-4-yl)methyl)-4-(3,4,5-trifluorophenyl)pyrrolidin-2-one) ([ 11 C]UCB-J) provides the opportunity to visualize synaptic density changes in vivo,… read more here.
Keywords: pet; ucb pet; model; autoradiography ... See more keywords
Measurement of Aβ Amyloid Plaques and Tau Protein in Postmortem Human Alzheimer’s Disease Brain by Autoradiography Using [18F]Flotaza, [125I]IBETA, [124/125I]IPPI and Immunohistochemistry Analysis Using QuPath
Sign Up to like & getrecommendations! Published in 2023 at "Biomedicines"
DOI: 10.3390/biomedicines11041033
Abstract: High-resolution scans of immunohistochemical (IHC) stains of Alzheimer’s disease (AD) brain slices and radioligand autoradiography both provide information about the distribution of Aβ plaques and Tau, the two common proteinopathies in AD. Accurate assessment of… read more here.
Keywords: 18f flotaza; brain; plaques tau; autoradiography ... See more keywords
Quantitative biodistribution of biotherapeutics at whole body, organ and cellular levels by autoradiography.
Sign Up to like & getrecommendations! Published in 2018 at "Bioanalysis"
DOI: 10.4155/bio-2018-0046
Abstract: AIM Tools for mapping and quantifying monoclonal antibody (mAb) and peptide biotherapeutics distribumtion were evaluated by comparing data from three independent methods conducted at the whole body, organ or tissue, and cellular levels. MATERIALS &… read more here.
Keywords: whole body; body organ; autoradiography; quantitative biodistribution ... See more keywords