T-bet-expressing B cells contribute to the autoreactive plasma cell pool in Lyn-/- mice.
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DOI: 10.1002/eji.202250300
Abstract: Systemic Lupus Erythematosus (SLE) is characterized by pathogenic autoantibodies against nucleic acid-containing antigens. Understanding which B cell subsets give rise to these autoantibodies may reveal therapeutic approaches for SLE that spare protective responses. Mice lacking… read more here.
Keywords: autoreactive plasma; cell; bet cells; lyn mice ... See more keywords