Avelumab for the treatment of locally advanced or metastatic Merkel cell carcinoma-A multicenter real-world experience in Israel.
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DOI: 10.1002/cam4.5890
Abstract: BACKGROUND Merkel cell carcinoma (MCC) is a rare and aggressive malignancy of the skin, affecting predominantly the fair-skinned older population exposed to high levels of ultraviolet light. Immune suppression is considered a significant risk factor.… read more here.
Keywords: cell carcinoma; merkel cell; avelumab; treatment ... See more keywords
Clinical Evaluation of Avelumab in the Treatment of Advanced Urothelial Carcinoma: Focus on Patient Selection and Outcomes
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DOI: 10.2147/cmar.s227323
Abstract: Background First-line therapy for treatment of advanced urothelial carcinoma includes combination platinum-based chemotherapies, though resistance and long-term toxicity concerns to these regimens cause limitations in progression-free survival and overall survival. Maintenance treatment with an alternative… read more here.
Keywords: urothelial carcinoma; treatment advanced; advanced urothelial; avelumab ... See more keywords
Real-world clinical outcomes with first-line avelumab in locally advanced/metastatic Merkel cell carcinoma in the USA: SPEAR-Merkel.
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DOI: 10.2217/fon-2020-1250
Abstract: Aim: To assess clinical outcomes in patients with locally advanced (la) or metastatic (m) Merkel cell carcinoma (MCC) initiating first-line (1L) avelumab in a USA community oncology setting. Materials & methods: Adults with laMCC or… read more here.
Keywords: advanced metastatic; avelumab; clinical outcomes; merkel ... See more keywords