Aversion-resistant fentanyl self-administration in mice.
Sign Up to like & getrecommendations! Published in 2020 at "Psychopharmacology"
DOI: 10.1007/s00213-020-05722-6
Abstract: RATIONALE Animal models of compulsive drug use that continues despite negative consequences can be used to investigate the neural mechanisms of addiction. However, models of punished or aversion-resistant opioid self-administration are notably lacking. OBJECTIVES We… read more here.
Keywords: self administration; oral fentanyl; aversion resistant; quinine ... See more keywords
Perineuronal nets in the insula regulate aversion‐resistant alcohol drinking
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DOI: 10.1111/adb.12821
Abstract: One of the most pernicious characteristics of alcohol use disorder is the compulsion to drink despite negative consequences. The insular cortex controls decision making under conditions of risk or conflict. Cortical activity is tightly controlled… read more here.
Keywords: drinking; insula; aversion resistant; aversion ... See more keywords
Sexually dimorphic role for insular perineuronal nets in aversion-resistant alcohol consumption
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Psychiatry"
DOI: 10.3389/fpsyt.2023.1122423
Abstract: Compulsive alcohol drinking is a key symptom of alcohol use disorder (AUD) that is particularly resistant to treatment. An understanding of the biological factors that underly compulsive drinking will allow for the development of new… read more here.
Keywords: aversion resistant; consumption; aversion; mice ... See more keywords
Modeling Aversion Resistant Alcohol Intake in Indiana Alcohol-Preferring (P) Rats
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DOI: 10.3390/brainsci12081042
Abstract: With the substantial social and medical burden of addiction, there is considerable interest in understanding risk factors that increase the development of addiction. A key feature of alcohol use disorder (AUD) is compulsive alcohol (EtOH)… read more here.
Keywords: aversion resistant; preferring rats; etoh; etoh drinking ... See more keywords
Neurobiological Basis of Aversion-Resistant Ethanol Seeking in C. elegans
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DOI: 10.3390/metabo13010062
Abstract: Persistent alcohol seeking despite the risk of aversive consequences is a crucial characteristic of alcohol use disorders (AUDs). Therefore, an improved understanding of the molecular basis of alcohol seeking despite aversive stimuli or punishment in… read more here.
Keywords: aversion resistant; resistant ethanol; ethanol seeking; aversion ... See more keywords