1422. Comparative Monte-Carlo Analysis of Aztreonam-Avibactam vs. Ceftazidime–Avibactam Against Carbapenem-Resistant Gram-Negative Pathogens
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DOI: 10.1093/ofid/ofy210.1253
Abstract: Abstract Background The new β-lactamase inhibitor, avibactam (AVI), has recently been combined with ceftazidime (CAZ) as CAZ-AVI. AVI is also in Phase 3 clinical trials combined with aztreonam as ATM-AVI. Both drug combinations have similar… read more here.
Keywords: 100 100; caz avi; atm avi; avi ... See more keywords
Does genetic variation in a bitter taste receptor gene alter early smoking behaviors in adolescents and young adults?
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DOI: 10.1111/add.15871
Abstract: BACKGROUND AND AIMS Variation in the TAS2R38 taste receptor gene alters the ability to taste bitter compounds. We tested whether TAS2R38 variation influences early smoking behaviors in adolescence, a critical period of acquisition when taste… read more here.
Keywords: genetic variation; avi; taste; variation ... See more keywords
Resistance to Ceftazidime/Avibactam in Klebsiella pneumoniae KPC-Producing Isolates: A Real-Life Observational Study
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DOI: 10.3390/antibiotics12050820
Abstract: Abstract Background: Ceftazidime/avibactam (CAZ-AVI) resistance amongst Enterobacterales is worryingly increasing worldwide. Objectives: The aim of this study was to collect and describe real-life data on CAZ-AVI-resistant Klebsiella pneumoniae (KP) isolates in our University Hospital, with… read more here.
Keywords: avi; caz avi; group; resistance ... See more keywords
In Vitro Activities and Inoculum Effects of Ceftazidime-Avibactam and Aztreonam-Avibactam against Carbapenem-Resistant Enterobacterales Isolates from South Korea
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DOI: 10.3390/antibiotics9120912
Abstract: Ceftazidime-avibactam (CAZ-AVI) and aztreonam-avibactam (AZT-AVI) are novel antibiotic combinations active against multidrug-resistant Gram-negative pathogens. This study aimed to evaluate their in vitro activities and inoculum effects in carbapenem-resistant Enterobacterales (CRE), including carbapenemase-producing (CP)-CRE and non-CP-CRE.… read more here.
Keywords: carbapenem resistant; azt avi; avi; caz avi ... See more keywords