Nodulisporic acid produces direct activation and positive allosteric modulation of AVR-14B, a glutamate-gated chloride channel from adult Brugia malayi
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DOI: 10.1073/pnas.2111932119
Abstract: Significance Filarial nematodes affect millions of people globally and constitute a serious public health issue in tropical and subtropical regions. Ivermectin (IVM) is used in combination with other chemotherapeutic agents for treatment and control of… read more here.
Keywords: avr 14b; brugia malayi; glutamate gated; nodulisporic acid ... See more keywords