Comparative transcriptomics and genomics from Continuous Axenic Media growth identifies Coxiella burnetii intracellular Survival strategies.
Sign Up to like & getrecommendations! Published in 2023 at "Pathogens and disease"
DOI: 10.1093/femspd/ftad009
Abstract: Coxiella burnetii (Cb) is an obligate intracellular pathogen in nature and the causative agent of acute Q fever as well as chronic diseases. In an effort to identify genes and proteins crucial to their normal… read more here.
Keywords: genomics continuous; comparative transcriptomics; growth; coxiella burnetii ... See more keywords
Lipid A Has Significance for Optimal Growth of Coxiella burnetii in Macrophage-Like THP-1 Cells and to a Lesser Extent in Axenic Media and Non-phagocytic Cells
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2018.00192
Abstract: Lipid A is an essential basal component of lipopolysaccharide of most Gram-negative bacteria. Inhibitors targeting LpxC, a conserved enzyme in lipid A biosynthesis, are antibiotic candidates against Gram-negative pathogens. Here we report the characterization of… read more here.
Keywords: axenic media; burnetii; coxiella; growth ... See more keywords