Synthesis and characterisation of platinum(IV) polypyridyl complexes with halide axial ligands
Sign Up to like & getrecommendations! Published in 2019 at "Inorganica Chimica Acta"
DOI: 10.1016/j.ica.2019.118964
Abstract: Abstract A series of complexes of the type [Pt(PL)(AL)(X)2]2+ (where PL = 1,10-phenanthroline, 5-methyl-1,10-phenanthroline or 5,6-dimethyl-1,10-phenanthroline; AL = 1S,2S-diaminocyclohexane and, X = Cl, Br or I) with anticancer potency, were synthesised in a one pot reaction using N-halogensuccinimide (NXS) as both… read more here.
Keywords: polypyridyl complexes; synthesis characterisation; platinum polypyridyl; axial ligands ... See more keywords
Stability, Reduction, and Cytotoxicity of Platinum(IV) Anticancer Prodrugs Bearing Carbamate Axial Ligands: Comparison with Their Carboxylate Analogues.
Sign Up to like & getrecommendations! Published in 2020 at "Inorganic chemistry"
DOI: 10.1021/acs.inorgchem.0c01541
Abstract: Platinum(IV) complexes containing carboxylate and carbamate ligands at the axial position have been reported previously. A better understanding of the similarity and difference between the two types of ligands will provide us with new insights… read more here.
Keywords: anticancer prodrugs; carboxylate; stability; carbamate axial ... See more keywords
Understanding the Role of Axial Ligands in Modulating the Biopharmaceutical Outcomes of Cisplatin(IV) Derivatives.
Sign Up to like & getrecommendations! Published in 2022 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.1c00844
Abstract: Cisplatin is a platinum (Pt)-based anticancer drug with broad-scale clinical utility. However, due to its hydrophilic nature and high kinetic reactivity, it offers numerous drug delivery challenges. Limitations such as severe systemic toxicities, chemoresistance, extensive… read more here.
Keywords: role; axial ligands; cisplatin derivatives; cisplatin ... See more keywords
A synthetic tactic to substitute axial ligands in sterically demanding Ru(II)porphyrinates.
Sign Up to like & getrecommendations! Published in 2022 at "Dalton transactions"
DOI: 10.1039/d2dt01095j
Abstract: We report a synthetic strategy that allows for the preparation of sterically encumbered heteroleptic Ru(II)porphyrinates with the desired configuration of stable/inert and weak/labile axial ligands to direct reactions between substrates to exclusively occur at the… read more here.
Keywords: tactic substitute; substitute axial; axial ligands; sterically demanding ... See more keywords
Exploring the effect of Axial Ligands, Solvation, and Redox on Structure and Inter-Metal Communication in Fe3-EMACs
Sign Up to like & getrecommendations! Published in 2024 at "New Journal of Chemistry"
DOI: 10.1039/d4nj01164c
Abstract: In the present work, we have studied the effect of the axial ligands, solvation, and oxidation and reduction on the structure and the nature of the Fe-Fe bonding of [Fe3L3]... read more here.
Keywords: axial ligands; structure; ligands solvation; effect axial ... See more keywords
Game of ligands: tuning the photodynamic activity of P(V) porphyrins in aqueous media.
Sign Up to like & getrecommendations! Published in 2025 at "Dalton transactions"
DOI: 10.1039/d5dt00808e
Abstract: For developing novel photosensitizers (PS), three series of phosphorus(V) tetra-meso-aryl-substituted porphyrins, bearing varying numbers of pyridyl groups (0 to 2) and different axial ligands (-OH, -OEt, -OPrOH) are obtained. All complexes exhibit fluorescence in EtOH… read more here.
Keywords: tuning photodynamic; axial ligands; game ligands; ligands tuning ... See more keywords
Tuning Photochemical and Photophysical Properties of P(V) Phthalocyanines
Sign Up to like & getrecommendations! Published in 2023 at "Molecules"
DOI: 10.3390/molecules28031094
Abstract: The ability of P(V) phthalocyanines (Pcs) for efficient singlet oxygen (SO) generation was demonstrated for the first time by the example of unsubstituted and α- and β-octabutoxy-substituted P(V)Pcs with hydroxy, methoxy and phenoxy ligands in… read more here.
Keywords: photophysical properties; quantum yields; photochemical photophysical; axial ligands ... See more keywords