Identification of ICAT as an APC Inhibitor, Revealing Wnt-Dependent Inhibition of APC-Axin Interaction.
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DOI: 10.1016/j.molcel.2018.07.040
Abstract: Adenomatous polyposis coli (APC) and Axin are core components of the β-catenin destruction complex. How APC's function is regulated and whether Wnt signaling influences the direct APC-Axin interaction to inhibit the β-catenin destruction complex is… read more here.
Keywords: apc axin; catenin; apc; interaction ... See more keywords