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The JAK/STAT3 axis: A comprehensive drug target for solid malignancies.

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Published in 2017 at "Seminars in cancer biology"

DOI: 10.1016/j.semcancer.2017.06.001

Abstract: Intercellular communication between tumor cells, immune cells and the stroma characterises the tumor microenvironment, which is instrumental for establishing the ecological niche that fosters tumor growth and metastasis. While tumor cell intrinsic STAT3 signaling provides… read more here.

Keywords: axis comprehensive; stat3; stat3 axis; jak stat3 ... See more keywords