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AGE-RAGE axis culminates into multiple pathogenic processes: a central road to neurodegeneration

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Published in 2023 at "Frontiers in Molecular Neuroscience"

DOI: 10.3389/fnmol.2023.1155175

Abstract: Advanced glycation end-products (AGEs; e.g., glyoxal, methylglyoxal or carboxymethyl-lysine) are heterogenous group of toxic compounds synthesized in the body through both exogenous and endogenous pathways. AGEs are known to covalently modify proteins bringing about loss… read more here.

Keywords: axis culminates; age rage; rage; rage axis ... See more keywords